Amylin, also known as islet amyloid polypeptide (IAPP), is a peptide hormone co-secreted with insulin from the pancreatic beta cells in humans. The specific form referred to as "Amylin (1-13) (Human)" corresponds to a truncated version of the full-length peptide, which consists of the first 13 amino acids of the human amylin sequence. This peptide plays a crucial role in glucose metabolism by regulating postprandial blood sugar levels, inhibiting glucagon secretion, and promoting satiety. Amylin is known to form amyloid fibrils, which are associated with type 2 diabetes, as their accumulation can lead to beta-cell dysfunction. The CAS number 198328-30-2 identifies this specific peptide variant, which is utilized in research to study its biological functions and potential therapeutic applications. Overall, amylin's characteristics include its peptide structure, involvement in glucose homeostasis, and relevance to metabolic disorders, making it a significant focus in diabetes research.

AMYLIN (1-13) (HUMAN)

198328-30-2: Amylin, also known as islet amyloid polypeptide (IAPP), is a peptide hormone co-secreted with insulin from the pancreatic beta cells in humans. The specific form referred to as "Amylin (1-13) (Human)" corresponds to a truncated version of the full-length peptide, which consists of the first 13 amino acids of the human amylin sequence. This peptide plays a crucial role in glucose metabolism by regulating postprandial blood sugar levels, inhibiting glucagon secretion, and promoting satiety. Amylin is known to form amyloid fibrils, which are associated with type 2 diabetes, as their accumulation can lead to beta-cell dysfunction. The CAS number 198328-30-2 identifies this specific peptide variant, which is utilized in research to study its biological functions and potential therapeutic applications. Overall, amylin's characteristics include its peptide structure, involvement in glucose homeostasis, and relevance to metabolic disorders, making it a significant focus in diabetes research.

IAPP 1-13 does not form fibrils, the region could be involved in the binding of amylin to membranes.

Amylin (1-13) (human)

Amylin (1-13) is a biotinylated human amylin fragment. It is used as a peroxidase substrate for the detection of human amylin in an ELISA assay.

CAS 198328-30-2

AMYLIN (1-13) (HUMAN)

Amylin (1-13) (human)

Ref: 01-4039860

Amylin (1-13) (human)

Ref: 3D-FA109592