CAS 198481-32-2: Bazedoxifene
Description:Bazedoxifene is a selective estrogen receptor modulator (SERM) primarily used in the treatment of postmenopausal osteoporosis. It exhibits tissue-selective estrogenic activity, meaning it can mimic estrogen in some tissues while blocking its effects in others. This characteristic makes it beneficial for bone health without the associated risks of estrogen therapy, such as increased breast cancer risk. Bazedoxifene works by binding to estrogen receptors in bone tissue, promoting bone density and reducing the risk of fractures. Its chemical structure includes a phenolic group, which contributes to its receptor-binding properties. Bazedoxifene is typically administered orally and is often combined with conjugated estrogens in therapeutic regimens. The substance has undergone extensive clinical trials to evaluate its efficacy and safety profile, demonstrating a favorable outcome in improving bone mineral density and overall bone health in postmenopausal women. As with any medication, potential side effects and contraindications should be considered, and it is essential for patients to consult healthcare professionals before starting treatment.
Formula:C30H34N2O3
InChI:InChI=1S/C30H34N2O3/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31/h6-15,20,33-34H,2-5,16-19,21H2,1H3
InChI key:InChIKey=UCJGJABZCDBEDK-UHFFFAOYSA-N
SMILES:OC=1C=CC(=CC1)C2=C(C3=CC(O)=CC=C3N2CC4=CC=C(OCCN5CCCCCC5)C=C4)C
- Synonyms:
- 1-((4-(2-Hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol
- 1-[[4-[2-(Azepan-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methylindol-5-ol
- 1-{4-[2-(azepan-1-yl)ethoxy]benzyl}-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol
- 1H-Indol-5-ol, 1-((4-(2-(hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-
- Bazedoxifene
- Bazedoxifeno
- Bazedoxifeno [INN-Spanish]
- Conbriza
- Tse-424
- Unii-Q16Tt9C5Bk
- See more synonyms
- Way 140424
Brand | Product data | Purity | Price range | Estimated delivery |
---|---|---|---|---|
![]() | 1H-Indol-5-ol, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl- REF: IN-DA002BJOCAS: 198481-32-2 | 98% | To inquire | Thu 27 Mar 25 |
![]() | Bazedoxifene REF: TR-B129245CAS: 198481-32-2 | - - - | 391.00 €~2,357.00 € | Tue 08 Apr 25 |

1H-Indol-5-ol, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-
Ref: IN-DA002BJO
5mg | 200.00 € | ||
10mg | 299.00 € | ||
25mg | 539.00 € | ||
50mg | To inquire | ||
100mg | To inquire |

Bazedoxifene
Controlled ProductRef: TR-B129245
5mg | 391.00 € | ||
10mg | 690.00 € | ||
50mg | 2,357.00 € |