CAS 198481-33-3: Bazedoxifene acetate

Description: Bazedoxifene acetate is a selective estrogen receptor modulator (SERM) primarily used in the treatment of postmenopausal osteoporosis and for the management of menopausal symptoms. It functions by mimicking estrogen in certain tissues, such as bone, while acting as an estrogen antagonist in others, such as breast and uterine tissues, thereby reducing the risk of estrogen-related side effects. The compound is characterized by its ability to bind selectively to estrogen receptors, promoting bone density without stimulating breast or uterine tissue proliferation. Bazedoxifene acetate is typically administered orally and is often combined with conjugated estrogens in therapeutic regimens. Its pharmacokinetics indicate a favorable absorption profile, with metabolism primarily occurring in the liver. The substance is known for its efficacy in reducing the incidence of vertebral fractures and improving overall bone health in postmenopausal women. As with any medication, potential side effects may include hot flashes, muscle spasms, and gastrointestinal disturbances, necessitating careful consideration of patient history and risk factors before prescribing.

Formula: C₃₀H₃₄N₂O₃·C₂H₄O₂

InChI: InChI=1S/C30H34N2O3.C2H4O2/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31;1-2(3)4/h6-15,20,33-34H,2-5,16-19,21H2,1H3;1H3,(H,3,4)

InChI key: InChIKey=OMZAMQFQZMUNTP-UHFFFAOYSA-N

SMILES: O=C(O)C.OC=1C=CC(=CC1)C2=C(C3=CC(O)=CC=C3N2CC4=CC=C(OCCN5CCCCCC5)C=C4)C

Synonyms:

• 1-(4-(2-(azepan-1-yl)ethoxy)benzyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetate
• 1-(p-(2-(Hexahydro-1H-azepin-1-yl)ethoxy)benzyl)-2-(p-hydroxyphenyl)-3-methylindol-5-ol monoacetate (salt)
• 1-{4-[2-(azepan-1-yl)ethoxy]benzyl}-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetate (1:1)
• 1H-Indol-5-ol, 1-((4-(2-(hexahydro-1H-azepin-1-yl)ethoxy)phenyl)methyl)-2-(4-hydroxyphenyl)-3-methyl-, monoacetate (salt)
• 1H-Indol-5-ol, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-, acetate (1:1)
• Tse 424
• Unii-J70472Ud3D
• Viviant
• Way-140424
• Way-Tes 424
• Bazedoxifene acetate

Bazedoxifene Acetate

CAS: 198481-33-3

• Color and Shape: Neat

1H-Indol-5-ol, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-, acetate (1:1)

CAS: 198481-33-3

• Formula: C₃₂H₃₈N₂O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 530.6545

Bazedoxifene Acetate

CAS: 198481-33-3

• Formula: C₃₀H₃₄N₂O₃·C₂H₄O₂
• Color and Shape: Off-White Solid
• Molecular weight: 470.61 60.05

Bazedoxifene acetate

CAS: 198481-33-3

• Formula: C₃₀H₃₄N₂O₃·C₂H₄O₂
• Purity: (HPLC) ≥ 98.0%
• Color and Shape: White to beige powder
• Molecular weight: 530.64

Bazedoxifene Acetate

CAS: 198481-33-3

• Formula: C₃₀H₃₄N₂O₃·C₂H₄O₂
• Color and Shape: Neat
• Molecular weight: 530.65

Bazedoxifene acetate

CAS: 198481-33-3

Bazedoxifene acetate (WAY-TES 424) is a novel selective estrogen receptor modulator (SERM).

• Formula: C₃₂H₃₈N₂O₅
• Purity: 99.24%
• Color and Shape: Solid
• Molecular weight: 530.67

Bazedoxifene Acetate

CAS: 198481-33-3

Applications Bazedoxifene Acetate is a nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene Acetate is used …

• Formula: C₃₀H₃₄N₂O₃·C₂H₄O₂
• Color and Shape: Neat
• Molecular weight: 530.65

Bazedoxifene acetate

CAS: 198481-33-3

Bazedoxifene acetate is a selective estrogen receptor modulator (SERM) that prevents bone loss and reduces …

• Formula: C₃₂H₃₈N₂O₅
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 530.65 g/mol

Bazedoxifene Acetate

CAS: 198481-33-3

• Formula: C₃₀H₃₄N₂O₃C₂H₄O₂
• Molecular weight: 470.62 : 60.05