CAS 198561-07-8: FMOC-L-PROPARGYLGLYCINE
Description:FMOC-L-propargylglycine is a chemical compound that serves as a building block in peptide synthesis and is particularly notable for its role in the development of bioorthogonal reactions. It features a fluorenylmethoxycarbonyl (FMOC) protecting group, which is commonly used to protect amino groups during peptide synthesis, allowing for selective reactions. The propargyl group in its structure introduces an alkyne functionality, enabling it to participate in click chemistry, particularly with azides, facilitating the formation of stable triazole linkages. This compound is typically utilized in research and pharmaceutical applications, especially in the synthesis of peptides that require specific modifications or functionalization. Its stability under standard laboratory conditions makes it a valuable reagent in organic synthesis. Additionally, FMOC-L-propargylglycine is characterized by its solubility in organic solvents, which is advantageous for various synthetic procedures. As with all chemical substances, proper handling and safety precautions should be observed due to potential hazards associated with its use.
Formula:C20H17NO4
InChI:InChI=1S/C20H17NO4/c1-2-7-18(19(22)23)21-20(24)25-12-17-15-10-5-3-8-13(15)14-9-4-6-11-16(14)17/h1,3-6,8-11,17-18H,7,12H2,(H,21,24)(H,22,23)/t18-/m0/s1
InChI key:InChIKey=DJGMNCKHNMRKFM-SFHVURJKSA-N
SMILES:O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NC(C(=O)O)CC#C
- Synonyms:
- (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}pent-4-ynoic acid
- (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)pent-4-ynoic acid
- (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-pentynoic acid
- (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}pent-4-ynoic acid
- (S)-2-(Fmoc-Amino)-4-Pentynoic Acid
- 4-Pentynoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-
- 4-Pentynoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (S)-
- Fmoc-(S)-2-Propargylglycine
- Fmoc-<span class="text-smallcaps">L</span>-propargylglycine
- Fmoc-Pra-Oh
- See more synonyms
- N-Alpha-(9-Fluorenylmethoxycarbonyl)-(S)-2-Amino-4-Pentynoic Acid
- N-Alpha-(9-Fluorenylmethoxycarbonyl)-Propargylglycine
- N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-Propargylglycine
- Rarechem Bk Pt 0257