CAS 198561-81-8: Fmoc-N-methyl-O-benzyl-L-threonine
CAS 198561-81-8: Fmoc-N-methyl-O-benzyl-L-threonine
Description:Fmoc-N-methyl-O-benzyl-L-threonine is a synthetic amino acid derivative commonly used in peptide synthesis and drug development. It features a phenylmethoxy (Fmoc) protecting group, which is widely employed to protect the amino group during peptide synthesis. The presence of the N-methyl group enhances the compound's lipophilicity and can influence the conformation and biological activity of the resulting peptides. The benzyl ether protects the hydroxyl group of threonine, allowing for selective reactions without interfering with other functional groups. This compound is typically utilized in solid-phase peptide synthesis, where its stability under various reaction conditions is advantageous. Its unique structure contributes to the modulation of peptide properties, such as solubility and binding affinity, making it valuable in the design of therapeutic peptides. Overall, Fmoc-N-methyl-O-benzyl-L-threonine is an important building block in the field of medicinal chemistry and peptide research.
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