CAS 19875-60-6

lisuride hydrogen maleate

Description:

Lisuride hydrogen maleate is a chemical compound primarily known for its use in the treatment of Parkinson's disease and other movement disorders. It is a derivative of lisuride, which is a dopamine agonist, meaning it mimics the action of dopamine in the brain. The substance is typically encountered as a salt form, specifically the hydrogen maleate, which enhances its solubility and stability. Lisuride itself is characterized by its ability to stimulate dopamine receptors, thereby alleviating symptoms associated with dopamine deficiency. The compound is often administered in a pharmaceutical context, and its efficacy is linked to its pharmacological profile, which includes effects on serotonin receptors as well. In terms of physical properties, lisuride hydrogen maleate is usually presented as a white to off-white powder, and it is soluble in water and alcohol, making it suitable for various formulations. Safety and efficacy profiles are well-studied, and it is important to consider potential side effects and contraindications when used in clinical settings.

Formula: C₂₄H₃₀N₄O₅

InChI: InChI=1/C20H26N4O.C4H4O4/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14;5-3(6)1-2-4(7)8/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,18+;/m0./s1

SMILES: CN1[C@]2(C(C=3C=4C(C2)=CNC4C=CC3)=C[C@H](NC(N(CC)CC)=O)C1)[H].C(=C\C(O)=O)\C(O)=O

Synonyms:

• 1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea (2Z)-but-2-enedioate
• 1-((5R,8S)-6-Methyl-9,10-didehydro-8-ergolinyl)-3,3-diethylurea hydrogen maleate
• 3-(9,10-Didehydro-6-methylergolin-8-alpha-yl)-1,1-diethylurea maleate (1:1)
• 3-(9,10-Didehydro-6-methylergolin-8-yl)-1,1-diethylurea hydrogen maleate
• Apodel
• Cuvalit
• Dopergin
• Ergoline, urea deriv.
• Eunal
• Indolo[4,3-fg]quinoline, urea deriv.
• Lisuride Maleate
• Lysenyl
• Lysenyl bimaleate
• Lysenyl hydrogen maleate
• Revanil
• Urea, 3-(9,10-didehydro-6-methylergolin-8-alpha-yl)-1,1-diethyl-, maleate (1:1)
• Urea, 3-(9,10-didehydro-6-methylergolin-8α-yl)-1,1-diethyl-, maleate (1:1)
• Urea, N'-((8-alpha)-9,10-didehydro-6-methylergolin-8-yl)-N,N-diethyl-, (Z)-2-butenedioate
• Urea, N′-[(8α)-9,10-didehydro-6-methylergolin-8-yl]-N,N-diethyl-, (2Z)-2-butenedioate (1:1)
• Urea, N′-[(8α)-9,10-didehydro-6-methylergolin-8-yl]-N,N-diethyl-, (Z)-2-butenedioate (1:1)
• 3-(9,10-didehydro-6-methylergolin-8-alpha-yl)-1,1-diethyl-uremaleate(1:1)
• Lysuride maleate
• lysenylhydrogenmaleate
• lisuridemaleate
• lysenylbimaleate
• 3-(9,10-didehydro-6-methylergolin-8-alpha-yl)-1,1-diethylureamaleate(1:1)
• N'-[(8α)-9,10-Didehydro-6-methylergolin-8-yl]-N,N-diethylureamaleate
• 3-(9,10-didehydro-6-methylergolin-8-yl)-1,1-diethylureahydrogenmaleate
• N'-(9,10-Didehydro-6-methylergoline-8α-yl)-N,N-diethylurea·(Z)-2-butenedioic acid
• lisuridehydrogenmaleate
• Urea, N'-[(8a)-9,10-didehydro-6-methylergolin-8-yl]-N,N-diethyl-, (2Z)-2-butenedioate (1:1) (9CI)
• Urea, 3-(9,10-didehydro-6-methylergolin-8a-yl)-1,1-diethyl-, maleate (1:1) (8CI)
• R-(+)-LISURIDE HYDROGEN MALEATE

Lisuride (maleate)

CAS: 19875-60-6

Formula: C₂₄H₃₀N₄O₅

Color and Shape: Solid

Molecular weight: 454.5188

Ref: IN-DA002BQ8

Lisuride maleate

CAS: 19875-60-6

Lisuride maleate

Purity: ≥98%

Ref: 54-BUP22349

Lisuride maleate

CAS: 19875-60-6

Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.

Formula: C₂₄H₃₀N₄O₅

Purity: 99.85%

Color and Shape: Solid

Molecular weight: 454.52

Ref: TM-T8775

Lisuride Maleate

CAS: 19875-60-6

Applications Lisuride Maleate is a dopamine receptor agonist with additionally serotoninergic, adrenergic, and glutamate antagonistic properties. Treatment of Parkinsonism and other diseases associated with high level of prolactin.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zweckberger, K., et al.: Neurosci. Lett., 499, 189-193 (2011); Kvasnicka, F., et al.: J. Chromatogr. A, 1066, 255-258 (2005)

Formula: C₂₀H₂₆N₄O•C₄H₄O₄

Color and Shape: Neat

Molecular weight: 338.4511607

Ref: TR-L469078

Lisuride maleate

Controlled Product

CAS: 19875-60-6

Lisuride maleate is a dopamine receptor agonist that is used in the treatment of Parkinson's disease and other conditions. It is also used to treat congestive heart failure, male erectile dysfunction, and other conditions. Lisuride maleate has been shown to improve sexual function in men with Parkinson's disease. The drug may be used for treating female sexual dysfunction, although studies are needed to confirm this. Lisuride maleate can be administered orally or by injection. It is metabolized in the liver and excreted by the kidneys.

Formula: C₂₀H₂₆N₄O•C₄H₄O₄

Purity: Min. 95%

Molecular weight: 454.52 g/mol

Ref: 3D-FL24912