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CAS 198821-22-6

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Merimepodib

Description:
Merimepodib is a chemical compound known for its role as an antiviral agent, particularly in the context of research related to viral infections. It functions primarily as a selective inhibitor of the enzyme inosine monophosphate dehydrogenase (IMPDH), which is crucial for the de novo synthesis of purine nucleotides. By inhibiting this enzyme, Merimepodib disrupts the replication of certain viruses, making it a candidate for therapeutic applications against viral diseases. The compound has shown potential in preclinical studies, particularly against viruses such as hepatitis C and other RNA viruses. In terms of its chemical properties, Merimepodib is characterized by its specific molecular structure, which includes functional groups that contribute to its biological activity. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are important factors in determining its efficacy and safety profile in clinical settings. As research continues, Merimepodib may offer insights into novel antiviral strategies and contribute to the development of effective treatments for viral infections.
Formula:C23H24N4O6
InChI:InChI=1/C23H24N4O6/c1-30-20-10-17(5-6-19(20)21-12-24-14-32-21)27-22(28)26-16-4-2-3-15(9-16)11-25-23(29)33-18-7-8-31-13-18/h2-6,9-10,12,14,18H,7-8,11,13H2,1H3,(H,25,29)(H2,26,27,28)/t18-/m0/s1
InChI key:InChIKey=JBPUGFODGPKTDW-SFHVURJKSA-N
SMILES:O(C)C1=C(C=CC(NC(NC2=CC(CNC(O[C@H]3CCOC3)=O)=CC=C2)=O)=C1)C4=CN=CO4
Synonyms:
  • (3S)-tetrahydrofuran-3-yl [3-({[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]carbamoyl}amino)benzyl]carbamate
  • Carbamic acid, N-[[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-, (3S)-tetrahydro-3-furanyl ester
  • Carbamic acid, [[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-, (3S)-tetrahydro-3-furanyl ester
  • Carbamic acid, [[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-, tetrahydro-3-furanyl ester, (S)-
  • Merimepodib
  • Vi-21497
  • Vx-497
  • [(3S)-oxolan-3-yl] N-[[3-[[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]carbamoylamino]phenyl]methyl]carbamate
  • MeriMepodib, VI-21497, VX-497
  • MERIMEPODIB; VX497; VX-497; VX 497; MMP; VI21497; VI-21497; VI 21497
  • [[3-[[[[3-Methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]carbamic acid (3S)-tetrahydro-3-furanyl ester
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Found 4 products.