CAS 198904-31-3: Atazanavir
Description:Atazanavir is an antiretroviral medication primarily used in the treatment of HIV/AIDS. It belongs to the class of drugs known as protease inhibitors, which work by inhibiting the protease enzyme, crucial for the viral replication process. Atazanavir is characterized by its relatively high selectivity for HIV-1 protease, which helps minimize side effects compared to other protease inhibitors. The compound is typically administered in its sulfate salt form, enhancing its solubility and bioavailability. Atazanavir is known for its once-daily dosing regimen, which improves patient adherence to treatment. Common side effects may include gastrointestinal disturbances, skin rashes, and potential effects on liver function. It is also notable for its interaction with other medications, necessitating careful management of drug regimens. Atazanavir is often used in combination with other antiretroviral agents to achieve a more effective viral suppression. Overall, its unique pharmacological profile makes it a valuable option in the management of HIV infection.
Formula:C38H52N6O7
InChI:InChI=1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32+/m0/s1
InChI key:InChIKey=AXRYRYVKAWYZBR-GASGPIRDSA-N
SMILES:O=C(OC)NC(C(=O)NN(CC=1C=CC(=CC1)C2=NC=CC=C2)CC(O)C(NC(=O)C(NC(=O)OC)C(C)(C)C)CC=3C=CC=CC3)C(C)(C)C
- Synonyms:
- 1,14-Dimethyl (3S,8S,9S,12S)-3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-pentaazatetradecanedioate
- 2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-, dimethyl ester, (3S,8S,9S,12S)-
- 2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-, dimethyl ester, (3S-(3R*,8R*,9R*,12R*))-
- 2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, 1,14-dimethyl ester, (3S,8S,9S,12S)-
- ATV
- Atazanavir [INN:BAN]
- Bms 232632
- Cgp 73547
- Hsdb 7339
- Latazanavir
- See more synonyms
- Reyataz
- Unii-Qzu4H47A3S
- Zrivada
- methyl {(5S,10S,11S,14S)-11-benzyl-5-tert-butyl-10-hydroxy-15,15-dimethyl-3,6,13-trioxo-8-[4-(pyridin-2-yl)benzyl]-2-oxa-4,7,8,12-tetraazahexadecan-14-yl}carbamate (non-preferred name)
