CAS 198904-31-3

Atazanavir

Description:

Atazanavir is an antiretroviral medication primarily used in the treatment of HIV/AIDS. It belongs to the class of drugs known as protease inhibitors, which work by inhibiting the protease enzyme, crucial for the viral replication process. Atazanavir is characterized by its relatively high selectivity for HIV-1 protease, which helps minimize side effects compared to other protease inhibitors. The compound is typically administered in its sulfate salt form, enhancing its solubility and bioavailability. Atazanavir is known for its once-daily dosing regimen, which improves patient adherence to treatment. Common side effects may include gastrointestinal disturbances, skin rashes, and potential effects on liver function. It is also notable for its interaction with other medications, necessitating careful management of drug regimens. Atazanavir is often used in combination with other antiretroviral agents to achieve a more effective viral suppression. Overall, its unique pharmacological profile makes it a valuable option in the management of HIV infection.

Formula: C₃₈H₅₂N₆O₇

InChI: InChI=1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31+,32+/m0/s1

InChI key: InChIKey=AXRYRYVKAWYZBR-GASGPIRDSA-N

SMILES: N(CC1=CC=C(C=C1)C2=CC=CC=N2)(C[C@@H]([C@H](CC3=CC=CC=C3)NC([C@@H](NC(OC)=O)[C@](C)(C)C)=O)O)NC([C@@H](NC(OC)=O)[C@](C)(C)C)=O

Synonyms:

• 1,14-Dimethyl (3S,8S,9S,12S)-3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-pentaazatetradecanedioate
• 2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-, dimethyl ester, (3S,8S,9S,12S)-
• 2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-, dimethyl ester, (3S-(3R*,8R*,9R*,12R*))-
• 2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, 1,14-dimethyl ester, (3S,8S,9S,12S)-
• ATV
• Atazanavir [INN:BAN]
• Bms 232632
• Cgp 73547
• Hsdb 7339
• Latazanavir
• Reyataz
• Unii-Qzu4H47A3S
• Zrivada

Atazanavir

CAS: 198904-31-3

Formula: C₃₈H₅₂N₆O₇

Purity: >95.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 704.87

Ref: 3B-A3469

Atazanavir

CAS: 198904-31-3

Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.

Formula: C₃₈H₅₂N₆O₇

Purity: 98% - 99.95%

Color and Shape: Crystalline Solid

Molecular weight: 704.86

Ref: TM-T0100L

Atazanavir

CAS: 198904-31-3

Formula: C₃₈H₅₂N₆O₇

Purity: 95%

Color and Shape: Solid

Molecular weight: 704.8555

Ref: IN-DA0072OT

Atazanavir

CAS: 198904-31-3

Atazanavir

Purity: 98%

Molecular weight: 704.87g/mol

Ref: 54-OR1029887

Atazanavir

CAS: 198904-31-3

Formula: C₃₈H₅₂N₆O₇

Purity: ≥ 98.0% (dried basis)

Color and Shape: White, off-white or beige powder

Molecular weight: 704.86

Ref: 7W-GP7551

Atazanavir

CAS: 198904-31-3

Formula: C₃₈H₅₂N₆O₇

Color and Shape: White To Off-White Solid

Molecular weight: 704.87

Ref: 4Z-A-771

Atazanavir

CAS: 198904-31-3

Atazanavir

Purity: ≥98%

Molecular weight: 704.86g/mol

Ref: 54-BUP15023

Atazanavir

Controlled Product

CAS: 198904-31-3

Applications Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Antiviral.
References Palella, F.J. Jr., et al.: N. Engl. J. Med., 338(13), 853 (1998), Nolan, D., et al.: Drugs, 63(23), 2555 (2003), Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (2004), Wood, R., et al.: J. Acquir. Immune Defic. Syndr., 36, 684 (2004),

Formula: C₃₈H₅₂N₆O₇

Color and Shape: Beige

Molecular weight: 704.86

Ref: TR-A790051

Atazanavir - Bio-X ™

CAS: 198904-31-3

Atazanavir is an antiviral protease inhibitor, used in the anti-retroviral therapy of adult and sometimes paediatric patients infected with HIV. This drug inhibits the processing of viral Gag and Gag-pol polyproteins in HIV-1 infected cells by binding to the HIV-1 protease active site.

Formula: C₃₈H₅₂N₆O₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 704.86 g/mol

Ref: 3D-BA300025

Atazanavir

CAS: 198904-31-3

Atazanavir is a HIV-1 protease inhibitor, used in the anti-retroviral therapy of adult and sometimes paediatric patients infected with HIV. In in vitro studies with human pulmonary epithelial cells, atazanavir has been studied as a potential inhibitor of SARS-CoV-2 Mpro protease, with the aim of halting viral replication.

Formula: C₃₈H₅₂N₆O₇

Purity: Min. 95%

Color and Shape: White Beige Powder

Molecular weight: 704.86 g/mol

Ref: 3D-FA18006