CAS 199110-64-0

Fmoc-4-phenyl-Phe-OH

Description:

Fmoc-4-phenyl-Phe-OH, also known as Fmoc-4-phenylphenylalanine, is a derivative of phenylalanine that features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is primarily utilized in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the Fmoc group serves as a protective moiety for the amino group, allowing for selective deprotection and coupling reactions. The presence of the phenyl group at the para position enhances the hydrophobic character of the amino acid, which can influence the folding and stability of peptides. Fmoc-4-phenyl-Phe-OH is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its molecular structure allows for various applications in medicinal chemistry and biochemistry, particularly in the design of peptide-based drugs and in studies of protein interactions. Proper handling and storage conditions are essential to maintain its stability and reactivity during synthesis.

Formula: C₃₃H₃₀N₂O₆

InChI: InChI=1/C33H30N2O6/c34-29(31(36)37)17-20-9-13-22(14-10-20)23-15-11-21(12-16-23)18-30(32(38)39)35-33(40)41-19-28-26-7-3-1-5-24(26)25-6-2-4-8-27(25)28/h1-16,28-30H,17-19,34H2,(H,35,40)(H,36,37)(H,38,39)/t29-,30-/m0/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=N[C@@H](Cc1ccc(cc1)c1ccc(cc1)C[C@@H](C(=O)O)N)C(=O)O)O

Synonyms:

• Fmoc-L-4,4'-Biphenylphenylalanine
• Fmoc-L-4,4'-Biphenylalanine
• Fmoc-Bip(4,4')-OH

3-(4-Biphenylyl)-N-Fmoc-L-alanine, 95%

CAS: 199110-64-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₃₀H₂₅NO₄

Purity: 95%

Molecular weight: 463.52

Ref: 02-H52002

Fmoc-4-phenyl-Phe-OH

CAS: 199110-64-0

Bachem ID: 4027843.

Formula: C₃₀H₂₅NO₄

Purity: 98.8%

Color and Shape: White

Molecular weight: 463.53

Ref: 01-4027843

[1,​1'-​Biphenyl]​-​4-​propanoic acid, α-​[[(9H-​fluoren-​9-​ylmethoxy)​carbonyl]​amino]​-​, (αS)​-

CAS: 199110-64-0

Formula: C₃₀H₂₅NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 463.5238

Ref: IN-DA002BWM

4-Phenyl-L-phenylalanine, N-FMOC protected

CAS: 199110-64-0

4-Phenyl-L-phenylalanine, N-FMOC protected

Formula: C₃₀H₂₅NO₄

Purity: 95%

Color and Shape: white to off white powder

Molecular weight: 463.5238g/mol

Ref: 54-OR14632

Fmoc-Bip(4,4′)-OH

CAS: 199110-64-0

Purity: 97%

Molecular weight: 463.18

Ref: 10-F556403

Fmoc-p-phenyl-L-phenylalanine

CAS: 199110-64-0

Fmoc-p-phenyl-L-phenylalanine (FMPP) is a fluorescent probe that can be used to detect and diagnose damage in tissues. It is a small molecule that has been shown to bind to myocytes and cardiac tissues, specifically targeting skeletal and cardiac muscle. FMPP binds to the amino acid phenylalanine, which is found in high concentrations in cardiac tissue. This binding causes an increase in fluorescence, which can be detected by light microscopy or flow cytometry. FMPP has been used to detect damage in heart muscles of mice with dilated cardiomyopathy and also as a probe for myocardial infarctions in humans.

Formula: C₃₀H₂₅NO₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 463.52 g/mol

Ref: 3D-FF47982