CAS 19916-77-9

N2-METHYL-2'-DEOXYGUANOSINE

Description:

N2-Methyl-2'-deoxyguanosine, with the CAS number 19916-77-9, is a modified nucleoside that features a methyl group attached to the nitrogen atom at the 2 position of the guanine base. This compound is a derivative of 2'-deoxyguanosine, which is one of the four nucleosides that make up DNA. The methylation at the N2 position can influence the molecule's properties, including its stability and interaction with DNA polymerases, potentially affecting DNA replication and repair processes. N2-methyl-2'-deoxyguanosine is of interest in biochemical and pharmacological research, particularly in studies related to mutagenesis and the effects of alkylating agents. Its structural modifications can also serve as a model for understanding the mechanisms of DNA damage and repair. In terms of solubility, it is generally soluble in polar solvents, and its reactivity can vary based on the surrounding chemical environment. Overall, this compound plays a significant role in the study of nucleic acid chemistry and cellular processes.

Formula: C₁₁H₁₅N₅O₄

Synonyms:

• 2'-Deoxy-N2-methyl-D-guanosine

2′-Deoxy-N-methylguanosine

CAS: 19916-77-9

Formula: C₁₁H₁₅N₅O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 281.2679

Ref: IN-DA002BXG

2'-Deoxy-N2-methylguanosine

CAS: 19916-77-9

2'-Deoxy-N2-methylguanosine

Purity: ≥98%

Molecular weight: 281.27g/mol

Ref: 54-BUP21003

2''-Deoxy-N2-methylguanosine

CAS: 19916-77-9

Formula: C₁₁H₁₅N₅O₄

Purity: ≥ 95.0%

Color and Shape: White to off-white powder

Molecular weight: 281.27

Ref: 7W-GN9748

N2-Methyl-2’-deoxyguanosine

Controlled Product

CAS: 19916-77-9

Applications N2-Methyl-2’-deoxyguanosine is a product from the reaction of formaldehyde with exocyclic amino group of deoxyguanosine. Used as the template in primer extension reactions catalyzed by the Klenow fragment of Escherichia coli DNA polymerase I.
References Yasui, M., et al.: Nucleic Acids Res., 29, 1994-2001 (2001)

Formula: C₁₁H₁₅N₅O₄

Color and Shape: Neat

Molecular weight: 281.27

Ref: TR-M293035

2'-Deoxy-N2-methylguanosine

CAS: 19916-77-9

2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.

Formula: C₁₁H₁₅N₅O₄

Purity: 99.79%

Color and Shape: Solid

Molecular weight: 281.27

Ref: TM-TNU1167

2'-Deoxy-N2-methylguanosine

CAS: 19916-77-9

2'-Deoxy-N2-methylguanosine is a nucleoside with anticancer properties. It is a phosphoramidite, which is an analog of the natural nucleotide guanosine, where the 2'-hydroxyl group has been replaced by a methylene group. This compound is used in DNA synthesis and RNA synthesis. It can be used as a monophosphate or diphosphate. It also has antiviral and anti-inflammatory activities, as well as N2-methylamino moiety that can be used for the treatment of cancer and inflammatory diseases such as arthritis.

Formula: C₁₁H₁₅N₅O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 281.27 g/mol

Ref: 3D-ND06236