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CAS 19916-78-0

:

2-Amino-9-(2-deoxy-α-D-erythro-pentofuranosyl)-1,9-dihydro-6H-purin-6-one

Description:
2-Amino-9-(2-deoxy-α-D-erythro-pentofuranosyl)-1,9-dihydro-6H-purin-6-one, commonly known as Acyclovir, is an antiviral medication primarily used to treat infections caused by certain types of viruses, particularly herpes simplex virus and varicella-zoster virus. This compound features a purine base structure, which is characteristic of nucleosides, and it contains an amino group at the 2-position and a deoxyribose sugar moiety. Acyclovir is notable for its selective action against viral DNA polymerases, which allows it to inhibit viral replication while having minimal effects on host cell DNA synthesis. The compound is typically administered orally or intravenously and is well-absorbed in the gastrointestinal tract. Its pharmacokinetics include renal excretion, and it has a relatively short half-life. Acyclovir is generally well-tolerated, but potential side effects can include nausea, diarrhea, and, in rare cases, renal toxicity. Its development marked a significant advancement in antiviral therapy, providing effective treatment options for herpesvirus infections.
Formula:C10H13N5O4
InChI:InChI=1S/C10H13N5O4/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,6-/m0/s1
InChI key:InChIKey=YKBGVTZYEHREMT-JKUQZMGJSA-N
SMILES:O=C1C2=C(N(C=N2)[C@H]3O[C@H](CO)[C@@H](O)C3)NC(N)=N1
Synonyms:
  • 2'-Deoxy-D-Guanosine
  • 2'-Deoxyguanosine monohydrate
  • 2-Amino-9-(2-deoxy-α-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,9-dihydro-6H-purin-6-one
  • 2-amino-9-(2-deoxy-alpha-L-erythro-pentofuranosyl)-3,9-dihydro-6H-purin-6-one
  • 2-amino-9-(2-deoxypentofuranosyl)-3,9-dihydro-6H-purin-6-one
  • 2[-Deoxyguanosine hemihydrate
  • 6H-Purin-6-one, 2-amino-9-(2-deoxy-α-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,9-dihydro-
  • 9-(2'-Deoxy-Beta-D-Ribofuranosyl)Guanine
  • A-2'-deoxyguanosine
  • Deoxyguanosine
  • See more synonyms
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Found 3 products.
  • 2-Amino-9-((2R,4S,5S)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one
    Indagoo
    + Info

    2-Amino-9-((2R,4S,5S)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one

    CAS:
    Formula:C10H13N5O4
    Color and Shape:Solid
    Molecular weight:267.2413

    Ref: IN-DA002BXF

    ne
    To inquire
  • 2'-Deoxy-a-guanosine
    Biosynth
    + Info

    2'-Deoxy-a-guanosine

    CAS:
    2'-Deoxy-a-guanosine is a nucleoside that is modified by the substitution of its ribose sugar with deoxyribose. It is used in anticancer and antiviral research. This chemical has been shown to inhibit DNA synthesis and RNA polymerase activity. 2'-Deoxy-a-guanosine has also been shown to have an anti-inflammatory effect, which may be due to its inhibition of prostaglandin synthesis.
    Formula:C10H13N5O4
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:267.25 g/mol

    Ref: 3D-ND09163

    25mg
    342.00€
    50mg
    477.00€
    100mg
    694.00€
    250mg
    1,206.00€
    500mg
    2,011.00€
  • a-2’-Deoxyguanosine
    TRC
    + Info

    a-2’-Deoxyguanosine

    Controlled Product
    CAS:
    <p>Applications α-2’-Deoxyguanosine is a reagent that forms a β-furanose anomer of imidazolone when photosensitized in the presence of benzophenone.<br>References Vialas, C., et al.: J. Chem. Soc. Perkin Trans. I, 1201-1206 (1999)<br></p>
    Formula:C10H13N5O4
    Color and Shape:Neat
    Molecular weight:267.241

    Ref: TR-D242425

    100mg
    2,087.00€