Endo-BCN-PEG2-acid is a chemical compound characterized by its unique structure that incorporates a bicyclo[6.1.0]nonyne (BCN) moiety linked to a polyethylene glycol (PEG) chain and a carboxylic acid functional group. This compound is notable for its biocompatibility and solubility in aqueous environments, making it suitable for various biomedical applications, including drug delivery and bioconjugation. The BCN group allows for efficient click chemistry reactions, particularly with azides, facilitating the formation of stable covalent bonds in the presence of mild conditions. The PEG segment enhances the solubility and reduces immunogenicity, which is advantageous in therapeutic contexts. Additionally, the presence of the carboxylic acid group provides a site for further functionalization or conjugation with other biomolecules. Overall, endo-BCN-PEG2-acid is a versatile compound that combines the benefits of click chemistry with the favorable properties of PEG, making it a valuable tool in chemical biology and materials science.

endo-BCN-PEG2-acid is a PEG linker containing a BCN group and a terminal carboxylic acid. The BCN group can react with azide-tagged biomolecules. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

endo-BCN-PEG2-acid

1993134-72-7: Endo-BCN-PEG2-acid is a chemical compound characterized by its unique structure that incorporates a bicyclo[6.1.0]nonyne (BCN) moiety linked to a polyethylene glycol (PEG) chain and a carboxylic acid functional group. This compound is notable for its biocompatibility and solubility in aqueous environments, making it suitable for various biomedical applications, including drug delivery and bioconjugation. The BCN group allows for efficient click chemistry reactions, particularly with azides, facilitating the formation of stable covalent bonds in the presence of mild conditions. The PEG segment enhances the solubility and reduces immunogenicity, which is advantageous in therapeutic contexts. Additionally, the presence of the carboxylic acid group provides a site for further functionalization or conjugation with other biomolecules. Overall, endo-BCN-PEG2-acid is a versatile compound that combines the benefits of click chemistry with the favorable properties of PEG, making it a valuable tool in chemical biology and materials science.

Endo-bcn-peg2-acid

endo-BCN-PEG2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

CAS 1993134-72-7

endo-BCN-PEG2-acid

Endo-bcn-peg2-acid

Ref: IN-DA019DZ8

Endo-bcn-peg2-acid

Ref: 54-OR1074885

endo-BCN-PEG2-acid

Ref: TM-T15221