CAS 1995893-58-7

FEN1 Inhibitor C2

Description:

FEN1 Inhibitor C2, identified by its CAS number 1995893-58-7, is a chemical compound that serves as an inhibitor of the enzyme flap endonuclease 1 (FEN1). This enzyme plays a crucial role in DNA replication and repair processes, particularly in the removal of RNA primers during DNA synthesis. The inhibition of FEN1 can have significant implications in cancer therapy, as it may enhance the effectiveness of certain chemotherapeutic agents by disrupting the DNA repair mechanisms in cancer cells. The compound is characterized by its specific binding affinity to the FEN1 enzyme, which can be assessed through various biochemical assays. Additionally, FEN1 Inhibitor C2 may exhibit properties such as solubility in organic solvents and stability under physiological conditions, making it a candidate for further pharmacological studies. Its potential applications in oncology and molecular biology highlight the importance of understanding its structure-activity relationship and the mechanisms underlying its inhibitory effects on FEN1.

Formula: C₁₂H₁₂N₂O₃

Synonyms:

• FEN1 Inhibitor C2
• FEN1-IN-4
• 2,4(1H,3H)-Quinazolinedione, 1-(cyclopropylmethyl)-3-hydroxy-

1-(Cyclopropylmethyl)-3-hydroxyquinazoline-2,4(1H,3H)-dione

CAS: 1995893-58-7

Formula: C₁₂H₁₂N₂O₃

Purity: 99%

Molecular weight: 232.2353

Ref: IN-DA01KKPI

FEN1-IN-4

CAS: 1995893-58-7

FEN1-IN-4

Purity: ≥98%

Molecular weight: 232.24g/mol

Ref: 54-BUP05297

FEN1-IN-4

CAS: 1995893-58-7

FEN1-IN-4 (FEN1 Inhibitor C2) is an inhibitor of human flap endonuclease-1 (hFEN1)

Formula: C₁₂H₁₂N₂O₃

Purity: 98.24%

Color and Shape: Solid

Molecular weight: 232.24

Ref: TM-T8545

1-(Cyclopropylmethyl)-3-hydroxyquinazoline-2,4(1H,3H)-dione

CAS: 1995893-58-7

Purity: 99%

Molecular weight: 232.2389984

Ref: 10-F870385

FEN1-IN-4

CAS: 1995893-58-7

FEN1-IN-4 is a small-molecule inhibitor, which is a chemically synthesized compound designed to selectively bind and inhibit the activity of Flap Endonuclease 1 (FEN1), a crucial enzyme in DNA replication and repair processes. By targeting FEN1, FEN1-IN-4 effectively interferes with its role in maintaining genomic stability, thereby promoting synthetic lethality in cancer cells that rely heavily on DNA repair mechanisms.

Formula: C₁₂H₁₂N₂O₃

Purity: Min. 95%

Molecular weight: 232.23 g/mol

Ref: 3D-VED89358