CAS 199593-08-3

N4-Acetyl-5'-(Dimethoxytrityl)-2'-O-Methylcytidine

Description:

N4-Acetyl-5'-(Dimethoxytrityl)-2'-O-Methylcytidine is a modified nucleoside that plays a significant role in biochemical research, particularly in the synthesis of oligonucleotides and in the study of RNA. This compound features several key structural characteristics: it contains an acetyl group at the N4 position of the cytidine base, which enhances its stability and solubility. The dimethoxytrityl (DMT) group at the 5' position serves as a protective group, facilitating the synthesis of nucleic acids by preventing unwanted reactions during the coupling process. Additionally, the 2'-O-methyl modification contributes to increased resistance to nucleases, making it valuable for therapeutic applications. The presence of these modifications allows for improved binding affinity and specificity in various biological assays. Overall, N4-Acetyl-5'-(Dimethoxytrityl)-2'-O-Methylcytidine is a crucial tool in molecular biology, enabling researchers to explore nucleic acid functions and develop novel therapeutic strategies.

Formula: C₃₃H₃₅N₃O₈

Synonyms:

• N4-Acetyl-5'-O-DMT-2'-O-methyl-D-cytidine
• DMT-2'-OMe-Ac-C
• 5'-O-DMT-N4-Acetyl-2'-O-Methyl-cytidine

N4-Acetyl-5'-(dimethoxytrityl)-2'-o-methylcytidine

CAS: 199593-08-3

Formula: C₃₃H₃₅N₃O₈

Purity: 97%

Color and Shape: Solid

Molecular weight: 601.6463

Ref: IN-DA002C7W

DMT-OMe-rC(Ac)

CAS: 199593-08-3

DMT-OMe-rC(Ac)

Purity: 97%

Molecular weight: 601.65g/mol

Ref: 54-OR1005943

N4-Acetyl-5''-O-DMT-2''-O-methylcytidine

CAS: 199593-08-3

Ref: 7W-GN4046

N-(1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

CAS: 199593-08-3

Purity: 95%

Molecular weight: 601.656005859375

Ref: 10-F693889

N4-Acetyl-5'-O-DMT-2'-O-methylcytidine

CAS: 199593-08-3

N4-Acetyl-5'-O-DMT-2'-O-methylcytidine is a cytidine analogue that has been synthesized to be used as an enzyme-linked probe. It is labelled with biotin and can be detected by binding to an antibody which has been labelled with a fluorescent tag. Cytidine analogues are synthesized on a solid phase and then cleaved from the support material. The spacer arm is added to the 5' end of the nucleotide and the 3'-OH group is modified with 2'-O-methyl groups. N4-Acetyl-5'-O-DMT-2'-O-methylcytidine has been shown to be sensitive in techniques such as solid phase synthesis, nucleic acid research, and immunoassays.

Formula: C₃₃H₃₅N₃O₈

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 601.65 g/mol

Ref: 3D-NA03000