CAS 199593-09-4: N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

Description: N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a modified nucleoside phosphoramidite used primarily in the synthesis of oligonucleotides. This compound features several key characteristics: it contains a nucleobase (cytidine) modified at the 2' position with a methyl group, enhancing its stability and resistance to enzymatic degradation. The presence of the 5'-O-(4,4-dimethoxytrityl) group serves as a protective moiety, facilitating the synthesis of oligonucleotides by preventing premature reactions. The cyanoethyl group attached to the phosphoramidite moiety is crucial for the coupling reaction during oligonucleotide synthesis, allowing for the formation of phosphodiester bonds. Additionally, the N-acetyl group contributes to the overall solubility and stability of the compound. This phosphoramidite is typically utilized in automated synthesizers for the production of RNA or DNA sequences, making it valuable in research and therapeutic applications, including gene therapy and antisense oligonucleotide development.

Formula: C₄₂H₅₂N₅O₉P

Synonyms:

• 2'-O-Methyl-rC(N-Ac)Phosphoramidite
• 5'-O-DMT-2'-O-Me-rC(N-Ac)-3'-CEDPA
• 2'-OMe-Ac-C Phosphoramidite
• 2'-O-Methyl-N4-Acetyl-5'-O-DMT-Cytidine-3'-CE-Phosphoramidite
• DMT-2-O-ME-C-CE Phosphoramidite

DMT-2'-O-methyl-rC(Ac) Phosphoramidite

CAS: 199593-09-4

• Formula: C₄₂H₅₂N₅O₉P
• Purity: >95.0%(qNMR)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 801.88

Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS: 199593-09-4

• Formula: C₄₂H₅₂N₅O₉P
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 801.8641

N4-Acetyl-5''-O-DMT-2''-O-methylcytidine 3''-CE phosphoramidite

CAS: 199593-09-4

2'-OMe-Ac-C Phosphoramidite

CAS: 199593-09-4

2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.

• Formula: C₄₂H₅₂N₅O₉P
• Color and Shape: Liquid
• Molecular weight: 801.86

2Õ-Ome-Ac-C Phosphoramidite

CAS: 199593-09-4

• Purity: 98%
• Molecular weight: 801.86g/mol

2'-OMe-Ac-C Phosphoramidite

CAS: 199593-09-4

• Molecular weight: 801.878

N4-Acetyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite

CAS: 199593-09-4

Please enquire for more information about N4-Acetyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite including the price, delivery time and …

• Formula: C₄₂H₅₂N₅O₉P
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 801.88 g/mol

2'-OMe-Ac-C Phosphoramidite (~90%)

CAS: 199593-09-4

Applications 2'-OMe-Ac-C Phosphoramidite (CAS# 199593-09-4) is a nucleotide used in the solid-phase synthesis of phosphorothioate …

• Formula: C₄₂H₅₂N₅O₉P
• Purity: ~90%
• Color and Shape: Neat
• Molecular weight: 801.88