CAS 199594-67-7

1-((2,6-Difluorophenyl)methyl)-4-methyl-2-(methylethyl)benzimidazole

Description:

1-((2,6-Difluorophenyl)methyl)-4-methyl-2-(methylethyl)benzimidazole, identified by its CAS number 199594-67-7, is a chemical compound that belongs to the class of benzimidazoles, which are known for their diverse biological activities. This compound features a benzimidazole core substituted with a 2,6-difluorophenyl group and additional alkyl groups, contributing to its unique properties. The presence of fluorine atoms typically enhances lipophilicity and can influence the compound's pharmacokinetics and biological interactions. The methyl and methylethyl substituents may also affect the compound's solubility and stability. Benzimidazoles are often studied for their potential applications in pharmaceuticals, particularly as anti-parasitic, anti-cancer, and anti-inflammatory agents. The specific structural modifications in this compound may impart distinct biological activities, making it a subject of interest in medicinal chemistry. However, detailed studies would be necessary to fully elucidate its properties, including its mechanism of action, efficacy, and safety profile in biological systems.

Formula: C₁₈H₁₈F₂N₂

InChI: InChI=1/C18H18F2N2/c1-11(2)18-21-17-12(3)6-4-9-16(17)22(18)10-13-14(19)7-5-8-15(13)20/h4-9,11H,10H2,1-3H3

SMILES: CC(C)c1nc2c(C)cccc2n1Cc1c(cccc1F)F

Synonyms:

• 1H-Benzimidazole, 1-((2,6-difluorophenyl)methyl)-4-methyl-2-(1-methylethyl)-
• 1-(2,6-Difluorobenzyl)-2-isopropyl-4-methylbenzimidazole
• 1-(2,6-difluorobenzyl)-4-methyl-2-(1-methylethyl)-1H-benzimidazole

1H-Benzimidazole, 1-[(2,6-difluorophenyl)methyl]-4-methyl-2-(1-methylethyl)-

CAS: 199594-67-7

Formula: C₁₈H₁₈F₂N₂

Molecular weight: 300.3457

Ref: IN-DA002C7P

1-[(2,6-Difluorophenyl)Methyl]-4-Methyl-2-Propan-2-Ylbenzimidazole

Controlled Product

CAS: 199594-67-7

1-[(2,6-Difluorophenyl)Methyl]-4-Methyl-2-Propan-2-Ylbenzimidazole is a broad spectrum HIV drug that inhibits the HIV transcriptase. It binds to the active site of the enzyme and blocks the binding of nucleotides, preventing RNA synthesis. 1-[(2,6-Difluorophenyl)Methyl]-4-Methyl-2-Propan-2-Ylbenzimidazole has been shown to be effective against HIV in vitro and in vivo. This inhibitor has been shown to inhibit both wild type and mutant forms of HIV transcriptase by binding to the same region of the enzyme. The molecule also shows good activity against other types of viruses, including influenza virus, vesicular stomatitis virus and poliovirus.

Formula: C₁₈H₁₈F₂N₂

Purity: Min. 95%

Molecular weight: 300.35 g/mol

Ref: 3D-FD98108