CAS 19983-15-4

4,5-Dihydro-2-phenyl-4-thiazolecarboxylic acid

Description:

4,5-Dihydro-2-phenyl-4-thiazolecarboxylic acid is a heterocyclic compound characterized by its thiazole ring, which contains both sulfur and nitrogen atoms. This compound features a phenyl group attached to the thiazole, contributing to its aromatic properties. The presence of a carboxylic acid functional group (-COOH) indicates that it can participate in acid-base reactions and may exhibit acidic behavior in solution. The thiazole ring is known for its biological activity, making derivatives of this compound of interest in medicinal chemistry. Typically, compounds like this may exhibit properties such as antimicrobial, anti-inflammatory, or analgesic activities, depending on their specific structure and substituents. The molecular structure allows for potential interactions with biological targets, which can be explored in drug development. Additionally, the compound's solubility, stability, and reactivity can vary based on environmental conditions, such as pH and temperature. Overall, 4,5-Dihydro-2-phenyl-4-thiazolecarboxylic acid represents a class of compounds with diverse applications in pharmaceuticals and organic synthesis.

Formula: C₁₀H₉NO₂S

InChI: InChI=1S/C10H9NO2S/c12-10(13)8-6-14-9(11-8)7-4-2-1-3-5-7/h1-5,8H,6H2,(H,12,13)

InChI key: InChIKey=HOZQYTNELGLJMC-UHFFFAOYSA-N

SMILES: C(O)(=O)C1N=C(SC1)C2=CC=CC=C2

Synonyms:

• 2-Thiazoline-4-carboxylic acid, 2-phenyl-
• 4,5-Dihydro-2-phenyl-4-thiazolecarboxylic acid
• 2-Phenyl-2-thiazoline-4-carboxylic acid
• 2-Phenyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid
• 4-Thiazolecarboxylic acid, 4,5-dihydro-2-phenyl-

2-Phenyl-4,5-dihydrothiazole-4-carboxylic acid

CAS: 19983-15-4

Formula: C₁₀H₉NO₂S

Molecular weight: 207.2490

Ref: IN-DA002CD9

2-Phenyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid

CAS: 19983-15-4

2-Phenyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid is an intermediate in the biosynthesis of flavoproteins. It is synthesized by a nonribosomal peptide synthetase (NRPS) and then converted to an active form of the enzyme by excision of the thiazole moiety. This conversion is catalyzed by a flavoprotein. The reaction proceeds via oxidative hydrogenation reactions, which are catalysed by a cytochrome P450 reductase and NADPH. 2-Phenyl-4,5-dihydro-1,3-thiazole-4 carboxylic acid has been shown to be effective in vitro as an inhibitor of bleomycin hydrolase activity and as an inhibitor of hydrogenation reactions that produce hydrogen peroxide from hydroperoxides.

Formula: C₁₀H₉NO₂S

Purity: Min. 95%

Molecular weight: 207.25 g/mol

Ref: 3D-UAA98315