CAS 199859-58-0

7-Cyano-7-deaza-2'-deoxy guanosine

Description:

7-Cyano-7-deaza-2'-deoxyguanosine is a modified nucleoside that serves as an analog of deoxyguanosine, featuring a cyano group at the 7-position of the purine ring and a deaza substitution at the 7-position, which replaces the nitrogen atom typically found in guanosine. This compound is characterized by its unique structural modifications that influence its biochemical properties, including its ability to participate in nucleic acid synthesis and its potential role in molecular biology and medicinal chemistry. The presence of the cyano group can enhance its stability and alter its hydrogen bonding capabilities, which may affect its interactions with nucleic acids and enzymes. Additionally, 7-cyano-7-deaza-2'-deoxyguanosine is of interest in research related to antiviral and anticancer therapies, as it may exhibit unique pharmacological properties compared to its natural counterparts. Its CAS number, 199859-58-0, allows for precise identification in chemical databases and literature. Overall, this compound represents a valuable tool for studying nucleic acid function and developing novel therapeutic agents.

Formula: C₁₂H₁₃N₅O₄

Synonyms:

• 7-Cyano-7-deaza-2'-deoxy guanosine
• 2-Amino-7-(2-deoxy--D-ribofuranosyl)-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one
• 3H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile, 2-amino-7-(2-deoxy-β-D-erythro-pentofuranosyl)-4,7-dihydro-4-oxo-

7-Cyano-7-deaza-2'-deoxy  guanosine

CAS: 199859-58-0

Nucleoside Derivatives - 7-Deaza-purine nucleoside; 2’-Deoxy Toyocamycin

Formula: C₁₂H₁₃N₅O₄

Color and Shape: Solid

Molecular weight: 291.26

Ref: TM-TNU1028

7-Cyano-7-deaza-2’-deoxyguanosine

CAS: 199859-58-0

7-Cyano-7-deaza-2’-deoxyguanosine is a pyrrole nucleoside analog that has been shown to inhibit the replication of herpes simplex virus type 1 and 2 in human cell lines. 7-Cyano-7-deaza-2’-deoxyguanosine is a synthetic nucleoside analog that is structurally similar to deoxyadenosine, but with a cyanide group instead of an oxygen atom. This compound has been shown to have the same biochemical properties as deoxyadenosine, including inhibiting the incorporation of uridine into RNA and DNA. In addition, 7-Cyano-7-deaza-2’-deoxyguanosine inhibits the synthesis of proteins from amino acids by competitive inhibition of ribonucleotide reductase, which catalyzes the conversion of ribonucleotides to deoxyribonucleotides. The enzyme's function

Formula: C₁₂H₁₃N₅O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 291.26 g/mol

Ref: 3D-FC144697