CAS 199864-86-3

RS-127445 Hydrochloride

Description:

RS-127445 Hydrochloride is a chemical compound that belongs to the class of selective serotonin reuptake inhibitors (SSRIs). It is primarily researched for its potential applications in treating various psychiatric disorders, particularly depression and anxiety. The compound exhibits a high affinity for serotonin transporters, which facilitates the modulation of serotonin levels in the brain, thereby influencing mood and emotional regulation. RS-127445 Hydrochloride is characterized by its hydrochloride salt form, which enhances its solubility and stability in aqueous solutions, making it suitable for pharmaceutical formulations. The compound's molecular structure includes specific functional groups that contribute to its pharmacological activity. Additionally, it has undergone various preclinical studies to assess its efficacy and safety profile. As with many SSRIs, potential side effects may include gastrointestinal disturbances, changes in weight, and effects on sexual function, necessitating careful monitoring during therapeutic use. Overall, RS-127445 Hydrochloride represents a significant area of interest in the development of new antidepressant therapies.

Formula: C₁₇H₁₇ClFN₃

Synonyms:

• 2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine hydrochloride
• 4-(4-Fluoro-1-naphthyl)-6-isopropylpyriMidin-2-aMine
• 2-AMino-4-(4-fluoronaphth-1-yl)-6-isopropylpyriMidine Monohydrochloride
• 2-PyriMidinaMine, 4-(4-fluoro-1-naphthalenyl)-6-(1-Methylethyl)-, Monohydrochloride
• 4-(4-Fluoro-1-naphthalenyl)-6-(1-methylethyl)-2-pyrimidinamine monohydrochloride
• RS 127445 hydrochloride NEW
• MT 500 Hydrochloride

RS-127445 HCl

CAS: 199864-86-3

Formula: C₁₇H₁₇ClFN₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.7884

Ref: IN-DA002CEC

RS-127445 hydrochloride

CAS: 199864-86-3

RS-127445 hydrochloride

Purity: ≥98%

Molecular weight: 317.79g/mol

Ref: 54-BUP10815

RS-127445 hydrochloride

CAS: 199864-86-3

Formula: C₁₇H₁₆FN₃·HCl

Molecular weight: 317.79

Ref: 7W-GK7015

RS-127445 Hydrochloride

CAS: 199864-86-3

Formula: C₁₇H₁₆FN₃·HCl

Purity: >98.0%(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 317.79

Ref: 3B-R0221

RS-127445 hydrochloride

CAS: 199864-86-3

RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5).

Formula: C₁₇H₁₇ClFN₃

Purity: 99.48%

Color and Shape: Solid

Molecular weight: 317.79

Ref: TM-T7519

RS 127445 hydrochloride

CAS: 199864-86-3

A selective antagonist of serotonin 5-HT2B receptors, inhibiting inositol phosphate formation and calcium release. Blocks 5-HT-induced contraction in rat stomach fundus. Reduces fecal output in vivo, upon inhibition of 5-HT2B by RS 127445, demonstrating a potential role for this receptor in colonic motility. Inhibits visceral hypersensitivity induced by restraint stress or colonic inflammation.

Formula: C₁₇H₁₆FN₃·HCl

Purity: Min. 95%

Color and Shape: White To Yellow Solid

Molecular weight: 317.79 g/mol

Ref: 3D-BR165563