CAS 199915-38-3

Fmoc-Isothiocyanate

Description:

Fmoc-Isothiocyanate, with the CAS number 199915-38-3, is a chemical compound commonly used in organic synthesis, particularly in the field of peptide chemistry. It features a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized to protect amino groups during peptide synthesis. The isothiocyanate functional group (-N=C=S) is known for its reactivity, allowing it to form thioureas and other derivatives upon reaction with nucleophiles, such as amines and alcohols. Fmoc-Isothiocyanate is typically a solid at room temperature and is soluble in organic solvents like dichloromethane and dimethylformamide. Its stability under standard laboratory conditions makes it a valuable reagent for the selective modification of biomolecules. Additionally, the compound is sensitive to moisture and should be stored in a dry environment to maintain its integrity. Overall, Fmoc-Isothiocyanate is an important tool in synthetic organic chemistry, particularly for the development of peptide-based therapeutics and research applications.

Formula: C₁₆H₁₁NO₂S

InChI: InChI=1/C16H11NO2S/c18-16(17-10-20)19-9-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9H2

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=O)N=C=S

Synonyms:

• 9H-fluoren-9-ylmethyl isothiocyanatocarbonate
• Fmoc isothiocyanate

Fmoc-isothiocyanate

CAS: 199915-38-3

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 281.3299865722656

Ref: 10-F493280

Carbon(isothiocyanatidic) acid, 9H-fluoren-9-ylmethyl ester

CAS: 199915-38-3

Formula: C₁₆H₁₁NO₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 281.3290

Ref: IN-DA002CFR

Fmoc-isothiocyanate

CAS: 199915-38-3

Fmoc-isothiocyanate

Purity: 95%

Molecular weight: 281.33g/mol

Ref: 54-OR962013

Fmoc-isothiocyanate

CAS: 199915-38-3

Fmoc-isothiocyanate is an inhibitor of the enzyme glycogen synthase kinase-3 (GSK-3) and has been shown to be a potential therapeutic agent for inflammatory diseases such as rheumatoid arthritis. Fmoc-isothiocyanate has also been shown to inhibit the production of melanocortin, a growth factor that is associated with cancer cells, and it can be used as an antiviral agent. This compound also inhibits the production of certain inflammatory cytokines and growth factors, which are involved in autoimmune diseases such as hepatitis and trifluoroacetic acid. Fmoc-isothiocyanate inhibits the activity of antifungal agents by inhibiting their ability to bind to fungal cell walls. It is synthesized on a solid support using trifluoroacetic acid as a reagent.

Formula: C₁₆H₁₁NO₂S

Purity: Min. 95%

Color and Shape: White To Light (Or Pale) Yellow Solid

Molecular weight: 281.33 g/mol

Ref: 3D-FF38870