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CAS 199982-01-9

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L-BUTHIONINE SULFOXIDE

Description:
L-Buthionine sulfoximine (L-BSO) is a synthetic compound primarily recognized for its role as an inhibitor of the enzyme gamma-glutamylcysteine synthetase, which is crucial in the synthesis of glutathione, a vital antioxidant in cells. This compound is characterized by its ability to deplete cellular glutathione levels, thereby influencing oxidative stress and cellular responses to various stimuli. L-BSO is often utilized in research settings to study the effects of reduced glutathione on cellular processes, including apoptosis and drug resistance in cancer cells. It is typically presented as a white to off-white solid and is soluble in water and various organic solvents. The compound's mechanism of action and its effects on cellular metabolism make it a valuable tool in pharmacological and biochemical studies, particularly in understanding the role of oxidative stress in disease mechanisms. Safety data indicates that while it is generally handled with caution in laboratory settings, specific toxicity profiles should be reviewed before use.
Formula:C8H17NO3S
InChI:InChI=1/C8H17NO3S/c1-2-3-5-13(12)6-4-7(9)8(10)11/h7H,2-6,9H2,1H3,(H,10,11)/t7-,13?/m0/s1
SMILES:CCCCS(=O)CC[C@@H](C(=O)O)N
Synonyms:
  • (2S)-2-Amino-4-(butylsulfinyl)butanoic Acid
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