CAS 199999-60-5

H-TYR-CYS-TRP-SER-GLN-TYR-LEU-CYS-TYR-OH

Description:

The chemical substance with the name "H-TYR-CYS-TRP-SER-GLN-TYR-LEU-CYS-TYR-OH" is a peptide composed of a sequence of amino acids, specifically tyrosine (Tyr), cysteine (Cys), tryptophan (Trp), serine (Ser), glutamine (Gln), and leucine (Leu). This peptide is characterized by its specific arrangement of these amino acids, which can influence its biological activity and properties. The presence of multiple tyrosine residues suggests potential for interactions with various biological receptors or enzymes, while cysteine residues may form disulfide bonds, contributing to the peptide's structural stability. The peptide's terminal amine (H-) and hydroxyl (-OH) groups indicate it may have specific solubility and reactivity characteristics. Additionally, the CAS number 199999-60-5 uniquely identifies this compound in chemical databases, facilitating its study and application in research, particularly in fields like biochemistry and pharmacology. Overall, the characteristics of this peptide can be explored further through techniques such as mass spectrometry and chromatography to understand its function and potential therapeutic uses.

Formula: C₅₈H₇₃N₁₁O₁₅S₂

Synonyms:

• Wp9Qy
• Tumor Necrosis Factor-Alpha Antagonist
• Tnf-Alpha Antagonist
• H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH, (Disulfide bond)

TNF-α Antagonist

CAS: 199999-60-5

TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with

Formula: C₅₈H₇₁N₁₁O₁₅S₂

Color and Shape: Solid

Molecular weight: 1226.39

Ref: TM-T36127

H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH trifluoroacetate salt (Disulfide bond)

CAS: 199999-60-5

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Formula: C₅₈H₇₁N₁₁O₁₅S₂

Purity: Min. 95%

Molecular weight: 1,226.38 g/mol

Ref: 3D-FT111079

H-Tyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr-OH

CAS: 199999-60-5

The TNF-α antagonist WP9QY inhibited TNF-α mediated apoptosis and exhibited an IC₅₀ of 5 µM in the binding assay. YCWSQYLCY is the smallest peptidomimetic developed to date that might be used as a lead compound for the next generation of non-peptidic inhibitors. The name WP9QY arises from the binding to the site observed in the TNF-β/TNF-receptor(I) complex designated WP9 and the introduction of the amino acids Gln and Tyr.

Formula: C₅₈H₇₁N₁₁O₁₅S₂

Purity: 97.9%

Molecular weight: 1226.4

Ref: 01-4028287