CAS 2001-95-8

Valinomycin

Description:

Valinomycin is a cyclic ionophore antibiotic that is primarily known for its ability to selectively transport potassium ions across lipid membranes. It is composed of a 12-membered lactone ring formed by the condensation of several amino acids, including valine, which gives it its name. Valinomycin exhibits a high affinity for K+ ions due to its unique structure, which allows it to encapsulate the ion effectively, facilitating its movement through biological membranes. This property makes valinomycin a valuable tool in biochemical research, particularly in studies involving ion transport and membrane potential. Additionally, valinomycin has been shown to exhibit antimicrobial activity against various microorganisms. Its mechanism of action involves disrupting the ionic balance within cells, leading to cell death. Valinomycin is soluble in organic solvents and has limited solubility in water, which influences its application in laboratory settings. Due to its potent biological effects, it is used in various experimental protocols, including studies on ion channels and cellular signaling pathways.

Formula: C₅₄H₉₀N₆O₁₈

InChI: InChI=1/C54H90N6O18/c1-22(2)34-49(67)73-31(19)43(61)55-38(26(9)10)53(71)77-41(29(15)16)47(65)59-36(24(5)6)51(69)75-33(21)45(63)57-39(27(11)12)54(72)78-42(30(17)18)48(66)60-35(23(3)4)50(68)74-32(20)44(62)56-37(25(7)8)52(70)76-40(28(13)14)46(64)58-34/h22-42H,1-21H3,(H,55,61)(H,56,62)(H,57,63)(H,58,64)(H,59,65)(H,60,66)/t31-,32-,33-,34+,35+,36?,37-,38-,39-,40+,41+,42+/m0/s1

Synonyms:

• 1,7,13,19,25,31-Hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone, 3,6,9,15,18,21,27,30,33-nonaisopropyl-12,24,36-trimethyl-
• Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl)
• Nsc 122023
• Valinomicin
• Valinomicina
• Valinomycine
• valinomicin[qr]
• VALINOMYCIN READY MADE SOLUTION
• aleryl-d-valyl-l-lactoyl-l-valyl-d-alpha-hydroxyisovaleryl-d-valyl-l-lactoyl-l
• CYCLO[-L-VAL-D-HYLVA-D-VAL-L-LAC-]3
• cyclic(d-alpha-hydroxyisovaleryl-d-valyl-l-lactoyl-l-valyl-d-alpha-hydroxyisov
• 1Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-
• akis(1-methylethyl)-[qr]
• Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid
• VALINOMYCIN 99%
• 3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-triMethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29,32,35-dodecone
• VALINOMYCIN >94% PURITY
• Valinomycin,90%
• ValinoMycin, froM StreptoMyces fulvissiMus
• 1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,
• hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl)
• Valinomycin,Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid
• 14,17,20,23,26,29,32,35-dodecone,12,24,36-trimetyl-3,6,9,15,18,21,27,30,33-non
• antibioticn-329b
• VALINOMYCINRESEARCH GRADE
• -valyl)[qr]
• nsc122023[qr]
• POTASSIUM IONOPHORE I
• Valinomycin,96%
• VALINOMYCIN, STREPTOMYCES FULVISSIMUS
• nsc122023
• Potassium ionophore I,Valinomycin
• VALINOMYCIN
• CYCLO(LAC-VAL-D-HIV-D-VAL-LAC-VAL-D-HIV-D-VAL-)

Valinomycin, 90+%

CAS: 2001-95-8

Potassium-selective ionophoric cyclodepsipeptide; inhibitor of mitochondrial action

Formula: C₅₄H₉₀N₆O₁₈

Purity: 90+%

Color and Shape: White, Powder or crystals or crystalline powder

Molecular weight: 1111.34

Ref: 02-J62312

Valinomycin

CAS: 2001-95-8

Valinomycin

Purity: ≥95%

Molecular weight: 1111.32g/mol

Ref: 54-BUP02178

Valinomycin

CAS: 2001-95-8

Formula: C₅₄H₉₀N₆O₁₈

Purity: ≥ 95%

Color and Shape: White powder

Molecular weight: 1111.34

Ref: 7W-GA5799

Valinomycin

CAS: 2001-95-8

Valinomycin

Formula: C₅₄H₉₀N₆O₁₈

Purity: By hplc: 100% (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 1,111.32g/mol

Ref: 54-BIV0893

Valinomycin

CAS: 2001-95-8

Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin

Formula: C₅₄H₉₀N₆O₁₈

Purity: 95.37% - 97.16%

Color and Shape: White Solid

Molecular weight: 1111.32

Ref: TM-TP1072

Valinomycin

Controlled Product

CAS: 2001-95-8

Applications K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction. Used as insecticide, nematocide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ivanov, et al.: Biochem. Biophys. Res. Commun., 34, 803 (1969), Duax, et al.: Science, 176, 911 (1972),

Formula: C₅₄H₉₀N₆O₁₈

Color and Shape: Neat

Molecular weight: 1111.32

Ref: TR-V094370

Valinomycin

CAS: 2001-95-8

Valinomycin is an ionophore antibiotic with action on potassium ion transport across cell membranes and is used for research on ion transport and as an antimicrobial agent.

Formula: C₅₄H₉₀N₆O₁₈

Purity: Min. 90 Area-%

Color and Shape: White Powder

Molecular weight: 1,111.32 g/mol

Ref: 3D-AV28656

Valinomycin, 95%

CAS: 2001-95-8

Formula: C₅₄H₉₀N₆O₁₈

Purity: min. 95%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 1111.3

Ref: SR-40652