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CAS 200335-40-6

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Fmoc-Asp-NH2

Description:
Fmoc-Asp-NH2, or Fluorenylmethoxycarbonyl aspartic acid amide, is a derivative of aspartic acid commonly used in peptide synthesis and research. It features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of the amino group during peptide synthesis. The presence of the amide group (-NH2) indicates that it is an amine derivative of aspartic acid, which is an important amino acid involved in protein synthesis and various metabolic processes. Fmoc-Asp-NH2 is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its stability under standard laboratory conditions makes it a valuable intermediate in the synthesis of peptides and other bioactive compounds. The Fmoc group can be removed under basic conditions, allowing for the subsequent coupling of other amino acids to form longer peptide chains. Overall, Fmoc-Asp-NH2 is a significant compound in the field of organic chemistry and biochemistry, particularly in the development of peptide-based therapeutics.
Formula:C19H18N2O5
InChI:InChI=1/C19H18N2O5/c20-18(24)16(9-17(22)23)21-19(25)26-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10H2,(H2,20,24)(H,21,25)(H,22,23)/t16-/m0/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=N[C@@H](CC(=O)O)C(=N)O)O
Synonyms:
  • N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alpha-asparagine
  • Fmoc-L-Isoasparagine
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