CAS 200354-35-4

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(2-hydroxyethyl)-L-cysteine

Description:

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(2-hydroxyethyl)-L-cysteine, commonly referred to as Fmoc-S-(2-hydroxyethyl)-L-cysteine, is a derivative of the amino acid cysteine, modified with a fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is characterized by its ability to protect the thiol group of cysteine during peptide synthesis, allowing for selective reactions without interference from the thiol functionality. The presence of the hydroxyethyl group enhances its solubility in polar solvents, making it suitable for various biochemical applications. Fmoc-S-(2-hydroxyethyl)-L-cysteine is often utilized in solid-phase peptide synthesis, where the Fmoc group can be easily removed under basic conditions, facilitating the sequential addition of amino acids. Its structural features contribute to its stability and reactivity, making it a valuable building block in the synthesis of peptides and proteins. Additionally, the compound's CAS number, 200354-35-4, serves as a unique identifier for regulatory and safety information in chemical databases.

Formula: C₂₀H₂₁NO₅S

InChI: InChI=1S/C20H21NO5S/c22-9-10-27-12-18(19(23)24)21-20(25)26-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,17-18,22H,9-12H2,(H,21,25)(H,23,24)/t18-/m0/s1

InChI key: InChIKey=VDIVFUTVJUGBOW-SFHVURJKSA-N

SMILES: C(OC(N[C@@H](CSCCO)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(2-hydroxyethyl)-
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(2-hydroxyethyl)-L-cysteine

Fmoc-Cys(2-hydroxyethyl)-OH

CAS: 200354-35-4

The ω-hydroxy group may be modified, e.g. esterified. S-Hydroxyethylcysteine is formed in blood proteins upon exposure to ethylene oxide. It has been isolated by Kubec et al. from the roots of Petiveria alliacea.

Formula: C₂₀H₂₁NO₅S

Purity: 98.5%

Color and Shape: White Powder

Molecular weight: 387.46

Ref: 01-4026001

L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(2-hydroxyethyl)-

CAS: 200354-35-4

Formula: C₂₀H₂₁NO₅S

Purity: 96%

Color and Shape: Solid

Molecular weight: 387.4494

Ref: IN-DA002CPY

N-(((9H-fluoren-9-yl)methoxy)carbonyl)-S-(2-hydroxyethyl)-L-cysteine

CAS: 200354-35-4

N-(((9H-fluoren-9-yl)methoxy)carbonyl)-S-(2-hydroxyethyl)-L-cysteine

Purity: 96%

Ref: 54-OR1042043

Fmoc-S-2-hydroxyethyl-L-cysteine

CAS: 200354-35-4

Molecular weight: 387.45

Ref: 7W-GM1517

FMOC-CYS(2-HYDROXYETHYL)-OH

CAS: 200354-35-4

Formula: C₂₀H₂₁NO₅S

Purity: 96%

Molecular weight: 387.45

Ref: 10-F475320