CAS 200432-86-6

(1R,6R)-2-(6-Chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-2-ene

Description:

The chemical substance known as (1R,6R)-2-(6-Chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-2-ene, with the CAS number 200432-86-6, is a bicyclic compound characterized by its unique structural framework, which includes a bicyclo[4.2.1]nonene core and a pyridine ring substituted with a chlorine atom. This compound exhibits chirality, indicated by the (1R,6R) configuration, which suggests specific spatial arrangements of its atoms that can influence its biological activity and interactions. The presence of the pyridine moiety often contributes to its potential as a pharmacological agent, as pyridine derivatives are commonly found in various therapeutic compounds. Additionally, the chlorine substituent may enhance lipophilicity and influence the compound's reactivity and binding properties. Overall, this substance is of interest in medicinal chemistry and may be studied for its potential applications in drug development or as a biochemical probe.

Formula: C₁₃H₁₅ClN₂

InChI: InChI=1S/C13H15ClN2/c14-13-7-4-9(8-15-13)11-3-1-2-10-5-6-12(11)16-10/h3-4,7-8,10,12,16H,1-2,5-6H2/t10-,12-/m1/s1

InChI key: InChIKey=TVSNVPGPFGAKPT-ZYHUDNBSSA-N

SMILES: ClC=1C=CC(C=2[C@@]3(N[C@@](CC3)(CCC2)[H])[H])=CN1

Synonyms:

• (1R,6R)-2-(6-Chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-2-ene
• 9-Azabicyclo[4.2.1]non-2-ene, 2-(6-chloro-3-pyridinyl)-, (1R)-
• 9-Azabicyclo[4.2.1]non-2-ene, 2-(6-chloro-3-pyridinyl)-, (1R,6R)-
• UB 165

UB 165

CAS: 200432-86-6

Formula: C₁₃H₁₅ClN₂

Molecular weight: 234.7246

Ref: IN-DA002CRY

Ub 165 fumarate

CAS: 200432-86-6

Ub 165 fumarate is an inhibitor of tumor proliferation. It has been shown to inhibit the growth of tumors in mice by inhibiting the production of flavanones, which are involved in tissue differentiation and cell growth. Ub 165 fumarate also inhibits retinopathy in a rat model by blocking the action of phosphodiesterase 4 (PDE4) enzyme. This drug was also found to be toxic for a variety of human cancer cells lines, including lung, prostate, colon, breast, and leukemia cells. The mechanism behind this activity is not yet understood and may involve inhibition of cyclin-dependent kinases or other downstream targets.

Formula: C₁₇H₁₉ClN₂O₄

Purity: Min. 95%

Molecular weight: 350.8 g/mol

Ref: 3D-AIA43286

UB 165

CAS: 200432-86-6

Subtype-selective nicotinic agonist

Formula: C₁₃H₁₅ClN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 234.72

Ref: TM-T23485