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CAS 200435-92-3

:

1-(2'-O,4-C-Methylene-beta-D-ribofuranosyl)uridine

Description:
1-(2'-O,4-C-Methylene-beta-D-ribofuranosyl)uridine, identified by its CAS number 200435-92-3, is a modified nucleoside that features a ribofuranosyl sugar moiety linked to a uridine base. This compound is characterized by the presence of a methylene bridge at the 4-position of the ribose, which enhances its stability and may influence its biological activity. The 2'-O substitution contributes to its resistance to enzymatic degradation, making it of interest in therapeutic applications, particularly in antiviral and anticancer research. The structural modifications can affect the nucleoside's interaction with nucleic acids and enzymes, potentially leading to altered pharmacokinetics and pharmacodynamics compared to unmodified nucleosides. Additionally, the compound may exhibit unique properties in terms of solubility and binding affinity, which are critical for its function in biological systems. Overall, this modified nucleoside represents a significant area of study in medicinal chemistry and molecular biology, with implications for drug design and development.
Formula:C10H12N2O6
Synonyms:
  • 1-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-2,4(1H,3H)-pyrimidinedione
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