CAS 200436-46-0

Leptin (150-167) (human)

Description:

Leptin is a hormone predominantly produced by adipose (fat) tissue, playing a crucial role in regulating energy balance, appetite, and metabolism. The specific form referred to as "Leptin (150-167) (human)" corresponds to a peptide fragment of the full-length leptin protein, which consists of 167 amino acids in humans. This fragment retains some biological activity and is involved in signaling pathways that influence hunger and energy expenditure. Leptin functions by binding to its receptor in the hypothalamus, leading to a decrease in appetite and an increase in energy expenditure. The CAS number 200436-46-0 identifies this specific peptide, which is used in research to study obesity, metabolic disorders, and related conditions. Leptin's structure includes a helical conformation, which is essential for its interaction with receptors. Dysregulation of leptin levels is associated with obesity and metabolic syndrome, making it a significant focus of biomedical research. Overall, leptin is a key player in the complex interplay of hormones that regulate body weight and energy homeostasis.

Formula: C₈₇H₁₃₈N₂₂O₂₈S₂

Synonyms:

• 37:PN: WO2008115880 SEQID: 35 claimed protein
• 8: PN: US20090281522 SEQID: 12 unclaimed protein
• Human150-167-leptin
• L-Cysteine, L-leucyl-L-glutaminylglycyl-L-seryl-L-leucyl-L-glutaminyl-L-a-aspartyl-L-methionyl-L-leucyl-L-tryptophyl-L-glutaminyl-L-leucyl-L-a-aspartyl-L-leucyl-L-seryl-L-prolylglycyl-
• H-Leu-Gln-Gly-Ser-Leu-Gln-Asp-Met-Leu-Trp-Gln-Leu-Asp-Leu-Ser-Pro-Gly-Cys-OH

Leptin tifluoroacetic acid (150-167)

CAS: 200436-46-0

Leptin tifluoroacetic acid (150-167) is a diagnostic agent that can be used to measure leptin in vivo. Leptin tifluoroacetic acid (150-167) is an agonist for the leptin receptor, which has been shown to have effects on locomotor activity, body weight and body mass index in animals. Leptin tifluoroacetic acid (150-167) has also been shown to have anti-inflammatory properties and may be of use in the treatment of bowel diseases such as inflammatory bowel disease or bowel disease. Leptin tifluoroacetic acid (150-167) binds with high affinity to human fat cells, allowing it to be used as a marker for fat cell differentiation and energy metabolism. The main function of leptin is regulation of food intake and energy expenditure by acting on receptors in the brain, liver, muscle and other tissues.

Formula: C₈₇H₁₃₈N₂₂O₂₈S₂•(CF₃CO₂H)x

Purity: Min. 95%

Molecular weight: 2,004.29 g/mol

Ref: 3D-FL109004