CAS 200484-11-3

2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine

Description:

2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine, with the CAS number 200484-11-3, is a chemical compound characterized by its complex structure, which includes a guanidine moiety, a cyano group, and a pyridine ring. This compound features a hexyl chain substituted with a 4-chlorophenoxy group, contributing to its lipophilicity and potential biological activity. The presence of the cyano group enhances its reactivity and may influence its interaction with biological targets. The pyridine ring can participate in hydrogen bonding and coordination with metal ions, which may be relevant in pharmacological contexts. This compound is of interest in medicinal chemistry, particularly for its potential applications in developing therapeutic agents. Its specific properties, such as solubility, stability, and biological activity, would depend on the molecular interactions and the environment in which it is studied. Overall, this compound exemplifies the complexity and diversity of organic molecules used in research and drug development.

Formula: C₁₉H₂₂ClN₅O

InChI: InChI=1/C19H22ClN5O/c20-16-5-7-18(8-6-16)26-14-4-2-1-3-11-23-19(24-15-21)25-17-9-12-22-13-10-17/h5-10,12-13H,1-4,11,14H2,(H2,22,23,24,25)

SMILES: C(CCCOc1ccc(cc1)Cl)CCN=C(NC#N)N=c1cc[nH]cc1

Synonyms:

• Chs-828

Guanidine, N-[6-(4-chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinyl-

CAS: 200484-11-3

Formula: C₁₉H₂₂ClN₅O

Purity: 98%

Color and Shape: Solid

Molecular weight: 371.8639

Ref: IN-DA002CSL

1-[6-(4-Chlorophenoxy)Hexyl]-3-Cyano-2-Pyridin-4-Ylguanidine

CAS: 200484-11-3

1-[6-(4-Chlorophenoxy)Hexyl]-3-Cyano-2-Pyridin-4-Ylguanidine

Purity: 98%

Molecular weight: 371.86g/mol

Ref: 54-OR1009305

CHS-828

CAS: 200484-11-3

CHS-828

Purity: ≥98%

Molecular weight: 371.86g/mol

Ref: 54-BUP05769

CHS-828

CAS: 200484-11-3

Formula: C₁₉H₂₂ClN₅O

Molecular weight: 371.9

Ref: 7W-GL8838

CHS-828

CAS: 200484-11-3

CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).

Formula: C₁₉H₂₂ClN₅O

Purity: 98% - 99.9%

Color and Shape: Solid

Molecular weight: 371.86

Ref: TM-T1998

GMX1778

Controlled Product

CAS: 200484-11-3

Applications GMX1778 is an anticancer agent that inhibits cellular synthesis of NAD.
References Olesen, U., et al.: Biochem. Biophys. Res. Commun., 367, 799 (2008); Watson, M., et al.: Mol. Cell. Biol., 29, 5872 (2009);

Formula: C₁₉H₂₂ClN₅O

Color and Shape: Neat

Molecular weight: 371.86

Ref: TR-G765050