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CAS 200616-39-3

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Fmoc-L-Glu(2-phenylisopropyloxy)-OH

Description:
Fmoc-L-Glu(2-phenylisopropyloxy)-OH is a derivative of the amino acid glutamic acid, modified to include a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group and a 2-phenylisopropyloxy side chain. This compound is typically used in peptide synthesis, particularly in solid-phase peptide synthesis, where the Fmoc group serves as a protective group for the amino group of the glutamic acid residue. The presence of the 2-phenylisopropyloxy moiety enhances the compound's hydrophobic characteristics, which can influence the solubility and stability of peptides during synthesis. The compound is characterized by its ability to participate in peptide bond formation while maintaining the integrity of the Fmoc group until deprotection is required. Its molecular structure contributes to its reactivity and compatibility with various coupling reagents used in peptide synthesis. Overall, Fmoc-L-Glu(2-phenylisopropyloxy)-OH is a valuable building block in the field of peptide chemistry, facilitating the synthesis of complex peptides with specific functional properties.
Formula:C29H29NO6
Synonyms:
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamic acid 5-(1-methyl-1-phenylethyl) ester
  • Fmoc-Glu(O-2-Phipr)-Oh
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