CAS 200815-49-2

Arformoterol tartrate

Description:

Arformoterol tartrate is a long-acting beta-2 adrenergic agonist primarily used in the management of chronic obstructive pulmonary disease (COPD) and asthma. It is the R-enantiomer of formoterol, which enhances its therapeutic efficacy. This compound acts by stimulating beta-2 adrenergic receptors in the bronchial smooth muscle, leading to bronchodilation and improved airflow. Arformoterol tartrate is typically administered via inhalation, allowing for direct delivery to the lungs, which maximizes its therapeutic effects while minimizing systemic side effects. The substance is characterized by its relatively long duration of action, providing sustained relief from bronchospasm. It is important to note that while arformoterol can improve lung function, it is not intended for the immediate relief of acute bronchospasm and should be used as part of a comprehensive treatment plan. As with other beta-agonists, potential side effects may include cardiovascular effects, tremors, and nervousness, necessitating careful monitoring in patients with pre-existing conditions.

Formula: C₂₃H₃₀N₂O₁₀

InChI: InChI=1/C19H24N2O4.C4H6O6/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22;5-1(3(7)8)2(6)4(9)10/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22);1-2,5-6H,(H,7,8)(H,9,10)/t13-,19+;1-,2-/m11/s1

Synonyms:

• (R,R)-Formoterol tartrate
• N-(2-Hydroxy-5-((1R)-1-hydroxy-2-(((1R)-2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)formamide (2R,3R)-2,3-dihydroxybutanedioate (1:1)
• Arformoterol Fumarate
• N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(1S)-2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl]phenyl}formamide 2,3-dihydroxybutanedioate (salt)
• N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl]phenyl}formamide 2,3-dihydroxybutanedioate (salt)
• Afromoterol tartrate

Formamide, N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)

CAS: 200815-49-2

Formula: C₂₃H₃₀N₂O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 494.4917

Ref: IN-DA002D1E

(R,R)-Formoterol L-Tartrate (Arformoterol L-Tartrate)

CAS: 200815-49-2

Formula: C₁₉H₂₄N₂O₄·C₄H₆O₆

Molecular weight: 344.41 150.09

Ref: 4Z-F-1128

Arformoterol Tartrate

CAS: 200815-49-2

Arformoterol Tartrate ((R,R)-Formoterol tartrate) is the tartrate salt of arformoterol.

Formula: C₂₃H₃₀N₂O₁₀

Purity: 99.98%

Color and Shape: Solid

Molecular weight: 494.49

Ref: TM-T22245

Arformoterol Tartrate

CAS: 200815-49-2

Applications Arformoterol Tartrate, can be used in the synthesis of Omeprazole (O635000), which is a proton pump inhibitor, that inhibits gasteric secretion, also used in the treatment of dyspepsia, peptic ulcer disease, etc. It is also the impurity of Esomeprazole Magnesium (E668300), which is the S-form of Omeprazole, and is a gastric proton-pump inhibitor. Also, It can be used for the preparation of olodaterol, a novel inhaled β2-adrenoceptor agonist with a 24h bronchodilatory efficacy.
References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998); Stenhoff, H., et al.: J. Chromatogr., 734, 191 (1999), Johnson, D.A., et al.: Expert Opin. Pharmacother., 4, 253 (2003); Bouyssou, T., et al.: Bio. Med. Chem. Lett. 20, 1410, (2010);

Formula: C₁₉H₂₄N₂O₄·C₄H₆O₆

Color and Shape: White To Light Brown

Molecular weight: 494.49

Ref: TR-A767505

Arformoterol tartrate - Bio-X ™

Controlled Product

CAS: 200815-49-2

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₉H₂₄N₂O₄•C₄H₆O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 494.49 g/mol

Ref: 3D-BA300007

Arformoterol tartrate

Controlled Product

CAS: 200815-49-2

Bronchodilator

Formula: C₁₉H₂₄N₂O₄•C₄H₆O₆

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 494.49 g/mol

Ref: 3D-BA171831

Arformoterol Tartrate-d6

Controlled Product

CAS: 200815-49-2

Formula: C₁₉D₆H₁₈N₂O₄·C₄H₆O₆

Color and Shape: Neat

Molecular weight: 500.529

Ref: TR-A767507

(R,R)-Formoterol L-Tartrate

CAS: 200815-49-2

Formula: C₁₉H₂₄N₂O₄C₄H₆O₆

Molecular weight: 344.41 : 150.09

Ref: ST-EA-CP-F42045

Arformoterol Tartrate

CAS: 200815-49-2

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

Formula: C₁₉H₂₄N₂O₄·C₄H₆O₆

Molecular weight: 344.17361

Ref: 45-1042340