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CAS 200880-42-8

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1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) monosodium salt

Description:
1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) monosodium salt, commonly referred to as DOPG, is a phospholipid that plays a significant role in cellular membranes and lipid bilayers. It is characterized by its two long-chain fatty acid tails, specifically octadecanoyl (stearic acid), which contribute to its hydrophobic properties, while the phosphate group provides a hydrophilic head. This amphiphilic nature allows DOPG to form bilayers in aqueous environments, making it essential for membrane structure and function. DOPG is often used in biophysical studies and drug delivery systems due to its ability to interact with proteins and other biomolecules. Its sodium salt form enhances its solubility in water, facilitating its use in various biochemical applications. Additionally, DOPG can influence membrane fluidity and permeability, making it a valuable compound in research related to membrane dynamics and cellular signaling. Overall, DOPG is a crucial component in the study of lipid interactions and membrane biology.
Formula:C42H83O10P·Na
InChI:InChI=1S/C42H83O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h39-40,43-44H,3-38H2,1-2H3,(H,47,48);/t39?,40-;/m1./s1
InChI key:InChIKey=IUBKCLFRZBJGPG-QTOMIGAPSA-N
SMILES:[C@@H](COP(OCC(CO)O)(=O)O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na]
Synonyms:
  • 1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt
  • 1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) monosodium salt
  • Octadecanoic acid, 1,1′-[(1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester, sodium salt (1:1)
  • Octadecanoic acid, (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, monosodium salt
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