CAS 20099-89-2

4-Cyanophenacyl bromide

Description:

4-Cyanophenacyl bromide is an organic compound characterized by its aromatic structure, which includes a phenacyl group and a cyano substituent. It is typically a white to light yellow crystalline solid that is soluble in organic solvents such as acetone and dichloromethane but has limited solubility in water. The presence of the bromide group makes it a reactive compound, often used in organic synthesis, particularly in the formation of various derivatives through nucleophilic substitution reactions. The cyano group contributes to its electronic properties, enhancing its reactivity and making it useful in the synthesis of pharmaceuticals and agrochemicals. Additionally, 4-Cyanophenacyl bromide can serve as a photoremovable protecting group in photochemistry due to its ability to undergo photolysis. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested, and appropriate protective equipment should be used.

Formula: C₉H₆BrNO

InChI: InChI=1S/C9H6BrNO/c10-5-9(12)8-3-1-7(6-11)2-4-8/h1-4H,5H2

InChI key: InChIKey=LJANCPRIUMHGJE-UHFFFAOYSA-N

SMILES: C(CBr)(=O)C1=CC=C(C#N)C=C1

Synonyms:

• 2-Bromo-1-(4-cyanophenyl)ethanone
• 2-Bromo-4'-cyano acetophenone
• 2-Bromo-4-cyanoacetophenone
• 2-Bromo-p-cyanoacetophenone
• 4-(2-Bromoacetyl)benzonitrile
• 4-(Bromoacetyl)Benzonitrile
• 4-Cyanophenacyl bromide
• Benzonitrile, 4-(2-bromoacetyl)-
• Benzonitrile, 4-(bromoacetyl)-
• Benzonitrile, p-(bromoacetyl)-
• NSC 157569
• p-Cyano-α-bromoacetophenone
• p-Cyano-ω-bromoacetophenone
• p-Cyanophenacyl bromide
• α-Bromo-4-cyanoacetophenone
• 4-Cyanophenacyl bromide 97%
• 4-CYANO 2-BROMO ACETOPHENONE
• cyanophenacylbromide
• BUTTPARK 41\03-55

4-Cyanophenacyl Bromide

CAS: 20099-89-2

Formula: C₉H₆BrNO

Purity: >96.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 224.06

Ref: 3B-C1348

Benzonitrile, 4-​(2-​bromoacetyl)​-

CAS: 20099-89-2

Formula: C₉H₆BrNO

Purity: 96%

Color and Shape: Solid

Molecular weight: 224.0540

Ref: IN-DA002D45

GSK-3 Inhibitor 5

CAS: 20099-89-2

4-Cyanophenacyl bromide, a ketone, used in drug-making and organic synthesis, blocks GSK-3.

Formula: C₉H₆BrNO

Purity: 99.58%

Color and Shape: Off-White To Light Yellow Crystalline Powder

Molecular weight: 224.05

Ref: TM-T77554

GSK-3 Inhibitor 5

CAS: 20099-89-2

GSK-3 Inhibitor 5

Purity: ≥98%

Molecular weight: 224.05g/mol

Ref: 54-BUP19651

4-(Bromoacetyl)benzonitrile

CAS: 20099-89-2

4-(Bromoacetyl)benzonitrile

Purity: 95%

Color and Shape: White Powder

Molecular weight: 224.05404g/mol

Ref: 54-OR29653

4-(2-Bromoacetyl)benzonitrile

CAS: 20099-89-2

Formula: C₉H₆BrNO

Purity: 97.0%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 224.057

Ref: 10-F018079

Isavuconazole Impurity 32 (4-Cyanophenacyl bromide)

CAS: 20099-89-2

Formula: C₉H₆BrNO

Molecular weight: 224.06

Ref: 4Z-I-070034

4-(2-Bromoacetyl)benzonitrile

Controlled Product

CAS: 20099-89-2

Applications 4-(2-Bromoacetyl)benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalomethylketones can be used in the study of novel GSK-3 inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Perez, D. et al.; J. Med. Chem. 54, 4042 (2011)

Formula: C₉H₆BrNO

Color and Shape: Neat

Molecular weight: 224.05

Ref: TR-B679275