CAS 2010-15-3

Phenylthiohydantoin

Description:

Phenylthiohydantoin (PTH) is a chemical compound characterized by its unique structure, which includes a hydantoin ring substituted with a phenylthio group. It is commonly used in biochemical applications, particularly in the field of amino acid analysis and protein sequencing, due to its ability to react with amino acids to form stable derivatives. PTH is typically synthesized through the reaction of phenyl isothiocyanate with amino acids, resulting in the formation of PTH-amino acid derivatives that can be easily identified and quantified. The compound is generally stable under standard laboratory conditions but may be sensitive to moisture and light. Its solubility varies depending on the solvent, with good solubility in organic solvents. PTH derivatives are often analyzed using chromatographic techniques, such as high-performance liquid chromatography (HPLC), making them valuable in analytical chemistry. Overall, phenylthiohydantoin serves as an important tool in the study of proteins and peptides, facilitating the identification and characterization of amino acid sequences.

Formula: C₉H₈N₂OS

InChI: InChI=1/C9H8N2O2S/c12-8-6-11(9(13)10-8)14-7-4-2-1-3-5-7/h1-5H,6H2,(H,10,12,13)

InChI key: InChIKey=ZZRIQDWDJVLELF-UHFFFAOYSA-N

SMILES: O=C1N(C(=S)NC1)C2=CC=CC=C2

Synonyms:

• 1-(Phenylsulfanyl)Imidazolidine-2,4-Dione
• 1-Phenyl-2-sulfanyl-4,5-dihydro-1H-imidazol-5-one
• 3-(Phenyl)thiohydantoin
• 3-N-Phenyl-2-thiohydantoin
• 3-Phenyl-2-Thioxoimidazolidin-4-One
• 3-Phenyl-2-sulfanylideneimidazolidin-4-one
• 3-Phenyl-2-thiohydantoin
• 3-Phenyl-2-thioxo-4-imidazolidinone
• 4-Imidazolidinone, 3-phenyl-2-thioxo-
• 4-Oxo-3-phenylimidazolidine-2-thione
• Glycine phenylthiohydantoin
• Glycine, 3-phenyl-2-thiohydantoin
• Hydantoin, 3-phenyl-2-thio-
• PTH-Glycine Phenylthiohydantoin-glycine
• Phenylthiohydantoin
• Phenylthiohydantoin-glycine
• PTH-GLYCINE
• PTH-glycine Standard
• 3-phenyl-2-thioguidanthion
• PHENYLTHIOHYDANTOIN-DL-GLYCINE
• 3-PHENYL-2-THIOXOTETRAHYDRO-4H-IMIDAZOL-4-ONE
• 3-phenyl-2-sulfanylidene-4-imidazolidinone
• PTH-DL-GLYCINE
• 2-Thioxo-3-phenylimidazolidine-4-one
• PTH-GLYCINE USP/EP/BP
• 3-phenyl-2-thio-hydantoi
• Phenylthiohydantoin-glycine&gt

Phenylthiohydantoin-glycine

CAS: 2010-15-3

Formula: C₉H₈N₂OS

Purity: >98.0%(HPLC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 192.24

Ref: 3B-P0376

4-Imidazolidinone, 3-phenyl-2-thioxo-

CAS: 2010-15-3

Formula: C₉H₈N₂OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 192.2376

Ref: IN-DA002D57

3-Phenyl-2-thioxoimidazolidin-4-one

CAS: 2010-15-3

3-Phenyl-2-thioxoimidazolidin-4-one

Purity: 97%

Molecular weight: 192.24g/mol

Ref: 54-OR76286

PTH-glycine

CAS: 2010-15-3

Formula: C₉H₈N₂OS

Molecular weight: 192.24

Ref: 7W-GK0568

2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one

CAS: 2010-15-3

Formula: C₉H₈N₂OS

Purity: 98%

Molecular weight: 192.24

Ref: 10-F358141

Phenylthiohydantoin-glycine

CAS: 2010-15-3

Phenylthiohydantoin-glycine is a drug used for the treatment of muscle diseases such as myasthenia gravis, Lambert-Eaton syndrome, and post-polio syndrome. It inhibits the production of acetylcholine at neuromuscular junctions by interfering with the synthesis of proteins that are critical for signal transmission from nerve cells to muscles. Phenylthiohydantoin-glycine is a small molecule consisting of two amino acids, phenylthiohydantoin and glycine. The drug binds to lysine residues on proteins using its hydroxyl group and trifluoroacetic acid moiety. This binding prevents the formation of an active enzyme that catalyzes the conversion of choline into acetylcholine at neuromuscular junctions.

Formula: C₉H₈N₂OS

Purity: Min. 95%

Molecular weight: 192.24 g/mol

Ref: 3D-CAA01015