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CAS 201484-12-0

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Fmoc-D-Dab-OH

Description:
Fmoc-D-Dab-OH, or 9-fluorenylmethoxycarbonyl-D-diaminobutyric acid, is a protected amino acid commonly used in peptide synthesis. It features a fluorenylmethoxycarbonyl (Fmoc) group, which serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The "D" in its name indicates that it is a D-enantiomer of diaminobutyric acid, which is important for the stereochemistry of peptides. This compound is typically white to off-white in appearance and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its stability under basic conditions makes it suitable for various synthetic applications, while its Fmoc group can be removed under mild basic conditions, facilitating the subsequent coupling of amino acids in solid-phase peptide synthesis. The presence of the diaminobutyric acid moiety allows for the introduction of additional functional groups, enhancing the versatility of the resulting peptides. Overall, Fmoc-D-Dab-OH is a valuable building block in the field of peptide chemistry.
Formula:C19H20N2O4
Synonyms:
  • N-α-Fmoc-D-2,4-diaminobutyric acid
  • (R)-2-(Fmoc-amino)-4-aminobutanoic acid
  • FMOC-D-ALPHA,GAMMA-DIAMINOBUTYRIC ACID
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl D-Dab-OH
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-ALPHA,GAMMA-DIAMINOBUTYRIC ACID
  • Nα-Fmoc-D-2,4-diaminobutyric acid≥ 99% (HPLC)
  • N-alpha-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N&gamma
  • Nα-Fmoc-D-2,4-diaminobutyric acid
  • FMOC-D-DAB-OH
  • N-ALPHA-(9-FLUOROENYLMETHYLOXYCARBONYL)-D-2,4-DIAMINOBUTYRIC ACID
  • See more synonyms
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