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CAS 201532-01-6

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Fmoc-D-Pen(Trt)-OH

Description:
Fmoc-D-Pen(Trt)-OH, with the CAS number 201532-01-6, is a chemical compound commonly used in peptide synthesis. It is an amino acid derivative featuring a phenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized for the protection of amine functionalities during the synthesis of peptides. The "D-Pen" refers to D-penicillamine, an amino acid that contains a penicillamine side chain, while "Trt" indicates the presence of a trityl protecting group on the side chain, which helps to protect the thiol group during synthesis. This compound is typically characterized by its stability under basic conditions and its ability to be deprotected under mild acidic conditions, allowing for selective removal of the protecting groups. Fmoc-D-Pen(Trt)-OH is valuable in the field of medicinal chemistry and biochemistry for the development of peptide-based therapeutics and research applications. Its structural features contribute to its utility in synthesizing complex peptide sequences while maintaining the integrity of sensitive functional groups.
Formula:C32H32N2O6
InChI:InChI=1/C32H32N2O6/c1-32(2,3)40-31(38)34-18-20(22-10-8-9-15-28(22)34)16-21(17-29(35)36)33-30(37)39-19-27-25-13-6-4-11-23(25)24-12-5-7-14-26(24)27/h4-15,18,21,27H,16-17,19H2,1-3H3,(H,33,37)(H,35,36)/t21-/m0/s1
SMILES:CC(C)(C)OC(=O)n1cc(C[C@@H](CC(=O)O)N=C(O)OCC2c3ccccc3c3ccccc23)c2ccccc12
Synonyms:
  • (3S)-4-[1-(tert-butoxycarbonyl)-1H-indol-3-yl]-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid
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