CAS 201594-84-5

(S)-2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine

Description:

(S)-2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine, with the CAS number 201594-84-5, is a chemical compound characterized by its specific stereochemistry and functional groups. It features a pyridine ring, which is a six-membered aromatic heterocycle containing one nitrogen atom. The compound includes a chlorophenyl group, which contributes to its lipophilicity and potential biological activity. The presence of a piperidinyloxy moiety suggests that it may interact with biological targets, possibly influencing neurotransmitter systems or other physiological pathways. This compound is likely to exhibit properties such as solubility in organic solvents, moderate stability under standard conditions, and potential reactivity due to the presence of the chlorophenyl and piperidine functionalities. Its stereochemistry (S configuration) may play a crucial role in its pharmacological profile, affecting how it interacts with biological receptors. Overall, this compound is of interest in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways.

Formula: C₁₇H₁₉ClN₂O

InChI: InChI=1/C17H19ClN2O/c18-14-6-4-13(5-7-14)17(16-3-1-2-10-20-16)21-15-8-11-19-12-9-15/h1-7,10,15,17,19H,8-9,11-12H2/t17-/m0/s1

SMILES: c1ccnc(c1)[C@H](c1ccc(cc1)Cl)OC1CCNCC1

Synonyms:

• 2-[(S)-(4-Chlorophenyl)-(4-piperidinyloxy)-methyl]-pyridine
• 2-[(S)-(4-chlorophenyl)(piperidin-4-yloxy)methyl]pyridine
• (S)-4-[1-(4-Chlorophenyl)-1-(2-pyridyl) methoxy] piperidine (for Bepotastine)
• (S)-4-[1-(4-Chlorophenyl)-1-(2-pyridyl) methoxy] piperidine
• Bepotastine Intermediate-1
• (S)-2-((4-chlorophenyl)(piperidin-4-yloxy)methyl)pyridine

Pyridine, 2-[(S)-(4-chlorophenyl)(4-piperidinyloxy)methyl]-

CAS: 201594-84-5

Formula: C₁₇H₁₉ClN₂O

Purity: 96%

Color and Shape: Liquid

Molecular weight: 302.7986

Ref: IN-DA002DIM

(S)-2-((4-Chlorophenyl)(piperidin-4-yloxy)methyl)pyridine

CAS: 201594-84-5

(S)-2-((4-Chlorophenyl)(piperidin-4-yloxy)methyl)pyridine

Purity: 99%

Molecular weight: 302.80g/mol

Ref: 54-OR95803

Bepotastine Impurity 5

CAS: 201594-84-5

Formula: C₁₇H₁₉ClN₂O

Molecular weight: 302.80

Ref: 4Z-B-5012

(S)-2-((4-Chlorophenyl)(piperidin-4-yloxy)methyl)pyridine

CAS: 201594-84-5

Purity: 95.0%

Molecular weight: 302.79998779296875

Ref: 10-F219885

(S)-2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine

Controlled Product

CAS: 201594-84-5

Applications (S)-2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine is used as a reagent to prepare optically active 4-[(4-chlorophenyl-2-pyridyl)methoxy]piperidine, a compound that is used as an intermediate in the synthesis of antihistamines and antiallergy agents. (S)-2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine is also an intermediate of Bepotastine besylate (B317000), a non-sedating H1-antagonist that has anti-inflammatory activity.
References Kita, J. Preparation of Optically Active 4-[(4-Chlorophenyl-2-pyridyl)methoxy]piperidine As A Material For Antihistamines and Antiallergy Agents. Jpn. Kokai Tokkyo Koho JP 10182635. Jul 7, 1998; Ohashi, R., et al.: Drug Metab. Disp., 34, 793 (2006)

Formula: C₁₇H₁₉ClN₂O

Color and Shape: Neat

Molecular weight: 302.8

Ref: TR-C380335