CAS 201677-61-4

Propanoic acid, 2,2-dimethyl-, 4-[[[2-[[(carboxymethyl)amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester, sodium salt, hydrate (1:1:4)

Description:

Propanoic acid, 2,2-dimethyl-, 4-[[[2-[[(carboxymethyl)amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester, sodium salt, hydrate (1:1:4), identified by CAS number 201677-61-4, is a complex organic compound characterized by its multi-functional structure. It features a propanoic acid backbone with additional functional groups, including sulfonamide and carboxymethyl amino groups, which contribute to its solubility and reactivity. As a sodium salt, it is likely to be soluble in water, making it suitable for various applications in biological and chemical contexts. The presence of multiple aromatic rings suggests potential for π-π interactions, which may influence its behavior in biological systems. The hydrate form indicates that it can associate with water molecules, affecting its stability and solubility. This compound may exhibit properties typical of both acids and amines, potentially allowing it to participate in a range of chemical reactions, including esterification and amide formation. Its specific applications would depend on its biological activity and interaction with other molecules, making it of interest in pharmaceutical and biochemical research.

Formula: C₂₀H₂₂N₂O₇S·4H₂O·Na

InChI: InChI=1S/C20H22N2O7S.Na.4H2O/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24;;;;;/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24);;4*1H2

InChI key: InChIKey=ZTSWBOROHLPTLV-UHFFFAOYSA-N

SMILES: C(NCC(O)=O)(=O)C1=C(NS(=O)(=O)C2=CC=C(OC(C(C)(C)C)=O)C=C2)C=CC=C1.[Na].O

Synonyms:

• (N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycinato-kappaO)sodium tetrahydrate
• Elaspol
• Elaspol 100
• Glycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate
• LY 544349 sodium tetrahydrate
• Propanoic Acid, 2,2-Dimethyl-, 4-[[[2-[[(Carboxymethyl)Amino]Carbonyl]Phenyl]Amino]Sulfonyl]Phenyl Ester, Sodium Salt, Hydrate (1:1:4)
• Sodium ({2-[({4-[(2,2-dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}amino)acetate hydrate (1:1:4)
• sodium, [2,2-dimethylpropanoato, 4-[[[2-[[[(carboxy-kappaO)methyl]amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester]-, hydrate (1:4)
• Sivelestat sodium tetrahydrate

Propanoic acid, 2,2-dimethyl-, 4-[[[2-[[(carboxymethyl)amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester, sodium salt, hydrate (1:1:4)

CAS: 201677-61-4

Formula: C₂₀H₂₉N₂NaO₁₁S

Purity: 95%

Color and Shape: Solid

Molecular weight: 528.5058

Ref: IN-DA002DKE

Sivelestat sodium tetrahydrate

CAS: 201677-61-4

Sivelestat sodium tetrahydrate

Purity: ≥98%

Molecular weight: 528.51g/mol

Ref: 54-BUP11018

Sivelestat sodium tetrahydrate

CAS: 201677-61-4

Sivelestat sodium tetrahydrate

Purity: 98%

Molecular weight: 528.51g/mol

Ref: 54-BISN0123

Sivelestat Sodium Tetrahydrate

CAS: 201677-61-4

Formula: C₂₀H₂₁N₂NaO₇S·4H₂O

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 528.50

Ref: 3B-I1240

Sivelestat sodium tetrahydrate

CAS: 201677-61-4

Sivelestat sodium tetrahydrate is a potent inhibitor of DNA polymerase, which plays an important role in the replication of bacterial and mammalian cells. It has been shown to bind to α7 nicotinic acetylcholine receptors and inhibit signaling pathways, such as the TLR4-dependent pathway. Sivelestat sodium tetrahydrate also inhibits elastase activity, which may be useful for treatment of inflammatory diseases. Sivelestat sodium tetrahydrate has been shown to have cardiac effects in mice and can lower blood pressure by inhibiting angiotensin converting enzyme (ACE) activity. Sivelestat sodium tetrahydrate is also known to be an effective inhibitor of neutrophil elastase and can be used for prevention of maternal blood loss during labor.

Formula: C₂₀H₂₂N₂O₇S•Na•(H₂₀)₄

Purity: Min. 95%

Molecular weight: 529.51 g/mol

Ref: 3D-FS153155

Sivelestat sodium tetrahydrate

CAS: 201677-61-4

Sivelestat sodium tetrahydrate (ONO5046 sodium tetrahydrate) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM.

Formula: C₂₀H₂₉N₂NaO₁₁S

Purity: 99.68%

Color and Shape: Solid

Molecular weight: 528.51

Ref: TM-T20762