CAS 202138-50-9: Tenofovir disoproxil fumarate

Description:Tenofovir disoproxil fumarate (TDF) is an antiretroviral medication primarily used in the treatment of HIV and chronic hepatitis B infections. It is a prodrug of tenofovir, which means it is metabolized in the body to its active form. TDF is characterized by its ability to inhibit the reverse transcriptase enzyme, thereby preventing viral replication. The compound is a white to off-white crystalline powder, soluble in water, and has a molecular formula that reflects its complex structure, including a fumarate salt. TDF is typically administered orally and is known for its favorable pharmacokinetic profile, allowing for once-daily dosing. It is often used in combination with other antiretroviral agents to enhance efficacy and reduce the risk of resistance. Common side effects may include renal impairment and bone mineral density loss, necessitating monitoring during treatment. Overall, Tenofovir disoproxil fumarate plays a crucial role in modern HIV therapy and is a key component of many treatment regimens.

Formula:C₂₃H₃₄N₅O₁₄P

InChI:InChI=1/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1+/t14-;/m1./s1

SMILES:O=C(O)C=CC(=O)O.O=C(OCOP(=O)(OCOC(=O)OC(C)C)COC(C)CN1C=NC=2C(=NC=NC21)N)OC(C)C

Synonyms:
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide, (R)-, (E)-2-butenedioate (1:1)
9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine fumarate
Gs 4331-05
PMPA Prodrug
Tenofovir DF
Tenofovir Dipivoxil Fumarate
Tenofovir Disproxil Fumarate
Virea
See more synonyms
Viread
bis({[(1-methylethoxy)carbonyl]oxy}methyl) {[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl}phosphonate (2E)-but-2-enedioate

Found 13 products.

Product data	Purity	Price range	Estimated delivery
Tenofovir disoproxil fumarate RS REF: 41-ICRS48744CAS: 202138-50-9	- - -	102.00 €	Tue 25 Mar 25
Tenofovir Disoproxil Fumarate REF: 45-1643656CAS: 202138-50-9	- - -	463.00 €	Wed 26 Mar 25
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1) REF: IN-DA002836CAS: 202138-50-9	99%	24.00 €~183.00 €	Thu 27 Mar 25
Tenofovir Disoproxil Fumarate REF: 4Z-T-022CAS: 202138-50-9	- - -	To inquire	Fri 28 Mar 25
Tenofovir disoproxil fumarate REF: 7W-GA7865CAS: 202138-50-9	≥ 98.0%	To inquire	Fri 28 Mar 25
Tenofovir Disoproxil Fumarate REF: 3B-T4062CAS: 202138-50-9	>95.0%(HPLC)(qNMR)	128.00 €	Tue 01 Apr 25
Tenofovir Disoproxil Fumarate REF: 86-MM1329.00CAS: 202138-50-9	- - -	928.00 €	Tue 01 Apr 25
Tenofovir disoproxil fumarate, 98% REF: AC-46125CAS: 202138-50-9	98%	To inquire	Tue 01 Apr 25
Tenofovir Disoproxil Fumarate REF: TM-T2409LCAS: 202138-50-9	98.60% - 99.02%	50.00 €~240.00 €	Thu 03 Apr 25
Tenofovir Disoproxil Fumarate REF: TR-T018505CAS: 202138-50-9	- - -	208.00 €~430.00 €	Tue 08 Apr 25
Tenofovir disoproxil fumarate - Bio-X ™ REF: 3D-BT164457CAS: 202138-50-9	Min. 95%	145.00 €	Mon 07 Apr 25
Tenofovir disoproxil fumarate REF: 3D-FT28031CAS: 202138-50-9	Min. 97.5 Area-%	172.00 €~1,436.00 €	Mon 07 Apr 25
Tenofovir Disoproxil-d6 Fumarate REF: TR-T018507CAS: 202138-50-9	- - -	405.00 €~2,745.00 €	Wed 07 May 25