CAS 202186-97-8

Guanosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2'-fluoro-

Description:

Guanosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2'-fluoro- is a modified nucleotide that plays a significant role in biochemical processes, particularly in the realm of molecular biology and biochemistry. This compound is characterized by the presence of a guanine base, a ribose sugar that has been modified to a 2'-deoxy form, and a triphosphate group. The substitution of a fluorine atom at the 2' position of the sugar enhances its stability and can influence its interactions with enzymes and nucleic acids. This modification can also affect the compound's ability to participate in biochemical reactions, making it a valuable tool in research, particularly in studies involving nucleic acid synthesis and manipulation. The triphosphate moiety is crucial for energy transfer and signaling in cellular processes. Overall, this compound exemplifies the intricate relationship between structure and function in nucleotides, highlighting the potential for chemical modifications to tailor biological activity.

Formula: C₁₀H₁₅FN₅O₁₃P₃

2'-Deoxy-2'-fluoroguanosine-5'-triphosphate tetralithium salt

CAS: 202186-97-8

2'-Deoxy-2'-fluoroguanosine-5'-triphosphate tetralithium salt is a chemically modified nucleotide used in molecular biology and pharmaceutical research. It is a guanosine analog featuring both a 2'-fluoro substitution on the sugar and a 5'-triphosphate group, with tetralithium as the counterion to improve solubility and stability.

Formula: C₁₀H₁₅FN₅O₁₃P₃·xLi

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 525.17 g/mol

Ref: 3D-ND09529

2'-Deoxy-2'-fluoroguanosine-5'-triphosphate lithium salt - 100mM aqueous solution

CAS: 202186-97-8

2'-Deoxy-2'-fluoroguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is an antiviral agent of the deoxyribonucleoside family. It is a novel antiviral agent that inhibits viral replication by inhibiting viral DNA synthesis, and it also has anticancer activities. 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is modified from guanosine monophosphate (GMP), which is a nucleotide precursor in DNA synthesis, and can be used as an activator for phosphoramidites in the synthesis of DNA.

Formula: C₁₀H₁₁FN₅O₁₃P₃Li₄

Purity: Min. 95%

Color and Shape: Liquid

Molecular weight: 548.9 g/mol

Ref: 3D-ND46153