CAS 202189-78-4

Bilastine

Description:

Bilastine is a second-generation antihistamine primarily used for the treatment of allergic conditions such as allergic rhinitis and urticaria. It is characterized by its selective antagonism of peripheral H1 histamine receptors, which helps alleviate symptoms like itching, sneezing, and runny nose without causing significant sedation, a common side effect associated with first-generation antihistamines. Bilastine has a favorable pharmacokinetic profile, exhibiting rapid absorption and a long half-life, allowing for once-daily dosing. It is also noted for its minimal interaction with cytochrome P450 enzymes, reducing the risk of drug-drug interactions. The substance is typically administered orally and is well-tolerated, with a safety profile that supports its use in various populations, including children and the elderly. Overall, bilastine represents a modern approach to managing allergic symptoms with a focus on efficacy and safety.

Formula: C₂₈H₃₇N₃O₃

InChI: InChI=1S/C28H37N3O3/c1-4-34-20-19-31-25-8-6-5-7-24(25)29-26(31)22-14-17-30(18-15-22)16-13-21-9-11-23(12-10-21)28(2,3)27(32)33/h5-12,22H,4,13-20H2,1-3H3,(H,32,33)

InChI key: InChIKey=ACCMWZWAEFYUGZ-UHFFFAOYSA-N

SMILES: C(COCC)N1C(=NC=2C1=CC=CC2)C3CCN(CCC4=CC=C(C(C(O)=O)(C)C)C=C4)CC3

Synonyms:

• 2-[-4-(2-[4-[1-(2-Ethoxyethyl)-1H-benzimidazol-2-yl]-1-piperidinyl]ethyl)phenyl]-2-methylpropanoic acid
• 2-[4-(2-{4-[1-(2-ethoxyethyl)-1H-benzimidazol-2-yl]piperidin-1-yl}ethyl)phenyl]-2-methylpropanoic acid
• 4-[2-[4-[1-(2-Ethoxyethyl)-1H-benzimidazol-2-yl]-1-piperidinyl]ethyl]-α,α-dimethylbenzeneacetic acid
• Benzeneacetic acid, 4-[2-[4-[1-(2-ethoxyethyl)-1H-benzimidazol-2-yl]-1-piperidinyl]ethyl]-α,α-dimethyl-
• Bilastine
• Labixten

Benzeneacetic acid, 4-[2-[4-[1-(2-ethoxyethyl)-1H-benzimidazol-2-yl]-1-piperidinyl]ethyl]-α,α-dimethyl-

CAS: 202189-78-4

Formula: C₂₈H₃₇N₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 463.6117

Ref: IN-DA002844

2-(4-(2-(4-(1-(2-EthoxyEthyl)-1H-Benzo[d]Imidazol-2-yl)Piperidin-1-yl)Ethyl)Phenyl)-2-mEthylpropanoic Acid

CAS: 202189-78-4

2-(4-(2-(4-(1-(2-EthoxyEthyl)-1H-Benzo[d]Imidazol-2-yl)Piperidin-1-yl)Ethyl)Phenyl)-2-mEthylpropanoic Acid

Purity: 99%

Molecular weight: 463.61g/mol

Ref: 54-OR1009739

Bilastine Impurity 5

CAS: 202189-78-4

Formula: C₂₀H₃₁N₃O₂

Color and Shape: White To Off-White Solid

Molecular weight: 345.49

Ref: 4Z-B-1710

Bilastine

CAS: 202189-78-4

Formula: C₂₈H₃₇N₃O₃

Color and Shape: White To Off-White Solid

Molecular weight: 463.62

Ref: 4Z-B-171

Bilastine

CAS: 202189-78-4

Bilastine

Purity: ≥98%

Molecular weight: 463.61g/mol

Ref: 54-BUP13883

Bilastine

CAS: 202189-78-4

Color and Shape: Neat

Ref: 86-MM3614.00

Bilastine

CAS: 202189-78-4

Formula: C₂₈H₃₇N₃O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 463.62

Ref: 3B-B5392

BILASTINE

CAS: 202189-78-4

Purity: 95%

Molecular weight: 463.622009277344

Ref: 10-F803285

Bilastine

CAS: 202189-78-4

Bilastine (Bilaxten) is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of

Formula: C₂₈H₃₇N₃O₃

Purity: 99.86% - >99.99%

Color and Shape: Solid

Molecular weight: 463.61

Ref: TM-T4250

4-[2-[4-[1-(2-Ethoxyethyl)-1H-benzimidazol-2-yl]-1-piperidinyl]ethyl]-a,a-dimethylbenzeneacetic acid

CAS: 202189-78-4

4-[2-[4-[1-(2-Ethoxyethyl)-1H-benzimidazol-2-yl]-1-piperidinyl]ethyl]-a,a-dimethylbenzeneacetic acid is a drug that belongs to the class of pharmacological agents. It is used to treat allergic symptoms and is intended for use in patients who are not responding to other therapies. This drug has been shown to be safe and effective in treating allergic rhinitis with or without conjunctivitis. The pharmacokinetics of 4-[2-[4-[1-(2-ethoxyethyl)-1H-benzimidazol-2-yl]-1-piperidinyl]ethyl]-a,a-dimethylbenzeneacetic acid are linear over the clinically relevant dose range and show no evidence of any significant interactions with other drugs. It has also been shown to have no effect on hepatic function or renal function in patients

Formula: C₂₈H₃₇N₃O₃

Purity: Min. 95%

Molecular weight: 463.61 g/mol

Ref: 3D-FE18595