CAS 2022-85-7
:Flucytosine
Description:
Flucytosine, with the CAS number 2022-85-7, is an antifungal medication primarily used to treat serious fungal infections, particularly those caused by Candida and Cryptococcus species. It is a pyrimidine analog that interferes with nucleic acid synthesis by inhibiting thymidylate synthase, ultimately disrupting fungal DNA and RNA synthesis. Flucytosine is typically administered in conjunction with other antifungal agents, such as amphotericin B, to enhance its efficacy and reduce the risk of resistance. The substance is well-absorbed when taken orally and is distributed widely throughout the body, including the central nervous system, making it effective for treating cryptococcal meningitis. Flucytosine is generally well-tolerated, but it can cause side effects such as bone marrow suppression and gastrointestinal disturbances. Its use requires careful monitoring of renal function and blood counts due to potential toxicity. Overall, flucytosine is a valuable tool in the antifungal arsenal, particularly for immunocompromised patients.
Formula:C4H4FN3O
InChI:InChI=1/C4H4FN3O/c5-8-2-1-3(6)7-4(8)9/h1-2H,(H2,6,7,9)
InChI key:InChIKey=XRECTZIEBJDKEO-UHFFFAOYSA-N
SMILES:NC1=C(F)C=NC(=O)N1
Synonyms:- 2(1H)-Pyrimidinone, 4-amino-5-fluoro-
- 2(1H)-Pyrimidinone, 6-amino-5-fluoro-
- 2-Hydroxy-4-Amino-5-Fluoropyrimidine
- 4-Amino-5-Fluoro-2(1H)-Pyrimidinone
- 4-Amino-5-fluoro-2(1H)-pyrmidinone
- 4-Amino-5-fluoropyrimidin-2(1H)-one
- 4-Amino-5-fluoropyrimidin-2-ol
- 4-amino-1-fluoropyrimidin-2(1H)-one
- 5-Flucytosine
- 5-Fluoro Cytosine
- 5-Fluorocystosine
- 5-Fluorocytosin
- 5-Fluorocytosine
- 6-Amino-2-oxo-5-fluoropyrimidine
- 6-Amino-5-fluoro-2(1H)-pyrimidinone
- 6-amino-5-fluoropyrimidin-2(1H)-one
- Alcobon
- Ancobon
- Ancotil
- Ancotyl
- Cytosine, 5-fluoro-
- Flucitosina
- Flucylosine
- Flucytosin
- Flucytosine
- Fluocytosine
- Nsc 103805
- Ro 2-9915
- Toca FC
- 5-FC
- TIMTEC-BB SBB000061
- 4-AMINO-5-FLUORO-3H-PYRIMIDIN-2-ONE
- FLUCYSTINE
- fluorocytosine
- 4-amino-5-fluoro-2(1h)-pyrimidinon
- 4-AMINO-5-FLUORO-2(1H)-PYRIMIDINE
- See more synonyms
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Found 22 products.
5-Fluorocytosine
CAS:Formula:C4H4FN3OPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:129.095-Fluorocytosine, 98+%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Formula:C4H4FN3OPurity:98+%Color and Shape:White, crystalline powderMolecular weight:129.09FLUCYTOSINE FOR SYSTEM SUITABILITY CRS
CAS:<p>FLUCYTOSINE FOR SYSTEM SUITABILITY CRS</p>Formula:C4H4FN3OMolecular weight:129.0925FLUCYTOSINE CRS
CAS:<p>FLUCYTOSINE CRS</p>Formula:C4H4FN3OColor and Shape:Crystalline Powder. White. Powder.Molecular weight:129.0925Flucytosine
CAS:<p>Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure</p>Formula:C4H4FN3OColor and Shape:White Off-White Crystalline PowderMolecular weight:129.033842(1H)-Pyrimidinone, 6-amino-5-fluoro-
CAS:Formula:C4H4FN3OPurity:95%Color and Shape:SolidMolecular weight:129.0925Flucytosine
CAS:<p>Flucytosine (NSC 103805) is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity.</p>Formula:C4H4FN3OPurity:98.76% - 99.28%Color and Shape:White Crystalline Solid SolidMolecular weight:129.095-Fluorocytosine
CAS:Formula:C4H4FN3OPurity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:129.095-Fluorocytosine
CAS:<p>5-Fluorocytosine</p>Formula:C4H4FN3OPurity:97%Color and Shape: off white powderMolecular weight:129.09g/mol5-Fluoro Cytosine
CAS:Controlled Product<p>Applications 5-FC is a toxic antifungal/antimicrobial agent.<br>References Gopinath, P., et al.: Biotechnol. Lett., 30, 1913 (2008), Kalkanci, A., et al.: Microbiol Immunol., 52, 435 (2008), Dubeau, M., et al.: App. Env. Microbiol., 75, 1211 (2009),<br></p>Formula:C4H4FN3OColor and Shape:White To Off-WhiteMolecular weight:129.09Cytosine-13C,15N2
CAS:Formula:CC3H515N2NOColor and Shape:Off-White To Light YellowMolecular weight:114.085-Fluorocytosine
CAS:<p>Flucytosine is an antifungal agent that inhibits the synthesis of DNA by preventing the conversion of deoxyuridine monophosphate to uracil monophosphate. It is used as an antiretroviral therapy in combination with other drugs, such as zidovudine and dideoxyinosine, to treat HIV infections. Flucytosine has been shown to have a strong antitumor response in a model system involving mice with sarcoma 180. This drug can cause serious side effects, including drug interactions and resistance mutations in microorganisms. These side effects are often observed in patients undergoing cancer chemotherapy or immunosuppressive therapy.</p>Formula:C4H4FN3OPurity:Min. 95%Color and Shape:White PowderMolecular weight:129.09 g/mol5-Fluorocytosine
CAS:Formula:C4H4FN3OPurity:98%Color and Shape:Solid, White powderMolecular weight:129.0945-Fluorocytosine (5-FCtys) extrapure, 98%
CAS:Formula:C4H4FN3OPurity:min. 98%Color and Shape:White, Crystalline powderMolecular weight:129.09
