CAS 2022-85-7

Flucytosine

Description:

Flucytosine, with the CAS number 2022-85-7, is an antifungal medication primarily used to treat serious fungal infections, particularly those caused by Candida and Cryptococcus species. It is a pyrimidine analog that interferes with nucleic acid synthesis by inhibiting thymidylate synthase, ultimately disrupting fungal DNA and RNA synthesis. Flucytosine is typically administered in conjunction with other antifungal agents, such as amphotericin B, to enhance its efficacy and reduce the risk of resistance. The substance is well-absorbed when taken orally and is distributed widely throughout the body, including the central nervous system, making it effective for treating cryptococcal meningitis. Flucytosine is generally well-tolerated, but it can cause side effects such as bone marrow suppression and gastrointestinal disturbances. Its use requires careful monitoring of renal function and blood counts due to potential toxicity. Overall, flucytosine is a valuable tool in the antifungal arsenal, particularly for immunocompromised patients.

Formula: C₄H₄FN₃O

InChI: InChI=1/C4H4FN3O/c5-8-2-1-3(6)7-4(8)9/h1-2H,(H2,6,7,9)

InChI key: InChIKey=XRECTZIEBJDKEO-UHFFFAOYSA-N

SMILES: NC1=C(F)C=NC(=O)N1

Synonyms:

• 2(1H)-Pyrimidinone, 4-amino-5-fluoro-
• 2(1H)-Pyrimidinone, 6-amino-5-fluoro-
• 2-Hydroxy-4-Amino-5-Fluoropyrimidine
• 4-Amino-5-Fluoro-2(1H)-Pyrimidinone
• 4-Amino-5-fluoro-2(1H)-pyrmidinone
• 4-Amino-5-fluoropyrimidin-2(1H)-one
• 4-Amino-5-fluoropyrimidin-2-ol
• 4-amino-1-fluoropyrimidin-2(1H)-one
• 5-Flucytosine
• 5-Fluoro Cytosine
• 5-Fluorocystosine
• 5-Fluorocytosin
• 5-Fluorocytosine
• 6-Amino-2-oxo-5-fluoropyrimidine
• 6-Amino-5-fluoro-2(1H)-pyrimidinone
• 6-amino-5-fluoropyrimidin-2(1H)-one
• Alcobon
• Ancobon
• Ancotil
• Ancotyl
• Cytosine, 5-fluoro-
• Flucitosina
• Flucylosine
• Flucytosin
• Flucytosine
• Fluocytosine
• Nsc 103805
• Ro 2-9915
• Toca FC
• 5-FC
• TIMTEC-BB SBB000061
• 4-AMINO-5-FLUORO-3H-PYRIMIDIN-2-ONE
• FLUCYSTINE
• fluorocytosine
• 4-amino-5-fluoro-2(1h)-pyrimidinon
• 4-AMINO-5-FLUORO-2(1H)-PYRIMIDINE

5-Fluorocytosine

CAS: 2022-85-7

Formula: C₄H₄FN₃O

Purity: 98%

Color and Shape: Solid, White powder

Molecular weight: 129.094

Ref: 10-F006215

5-Fluorocytosine (5-FCtys) extrapure, 98%

CAS: 2022-85-7

Formula: C₄H₄FN₃O

Purity: min. 98%

Color and Shape: White, Crystalline powder

Molecular weight: 129.09

Ref: SR-24245