CAS 20226-99-7

L-threo-Pentaric acid, 3-carboxy-2,3-dideoxy-, potassium salt (1:1)

CAS: 20226-99-7

Formula: C₆H₇KO₇

Purity: 98%

Molecular weight: 230.2139

Ref: IN-DA00285D

(+)-Potassium ds-threo-isocitrate monobasic

CAS: 20226-99-7

(+)-Potassium ds-threo-isocitrate monobasic is a dehydrogenase inhibitor that blocks the conversion of isocitrate to alpha-ketoglutarate, which is required for the production of energy. This drug can be used as a treatment for glioblastoma multiforme. (+)-Potassium ds-threo-isocitrate monobasic has been shown to inhibit tumor growth in vitro and in vivo. It inhibits glioma cell proliferation and migration, induces apoptosis, and inhibits angiogenesis. The inhibition of tumor growth by this drug may be due to its ability to inhibit the metabolism of isocitrate into alpha-ketoglutarate and ATP synthesis, which leads to elevated levels of reactive oxygen species (ROS). This drug also inhibits matrix metalloproteases (MMP) activity at high doses, but not at low doses.

Formula: C₆H₇KO₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 230.21 g/mol

Ref: 3D-VAA22699

(+)-Potassium Ds-threo-isocitrate monobasic

CAS: 20226-99-7

(+)-Potassium Ds-threo-isocitrate monobasic is a bioactive compound known for its role in enhancing cellular metabolism and regulating energy production. This substance is also utilized in researching metabolic pathways and the regulation of enzyme activities. Widely applied in biochemical research, (+)-Potassium Ds-threo-isocitrate monobasic is studied for its potential functions in cellular processes and disease mechanisms.

Formula: C₆H₇KO₇

Color and Shape: Solid

Molecular weight: 230.21

Ref: TM-T201097