CAS 202466-68-0

4-Amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]benzenesulfonamide

Description:

4-Amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]benzenesulfonamide, with the CAS number 202466-68-0, is a chemical compound that belongs to the class of sulfonamides, which are characterized by the presence of a sulfonamide functional group (-SO2NH2). This compound features an amino group (-NH2) and a pyrimidine ring, which contributes to its potential biological activity. It is typically a solid at room temperature and may exhibit solubility in polar solvents due to the presence of amino and sulfonamide groups. The structure suggests that it may interact with biological targets, potentially serving as a pharmaceutical agent. Compounds of this nature are often investigated for their antimicrobial or antitumor properties. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity or reactivity. Further studies would be necessary to fully elucidate its pharmacological profile and applications in medicinal chemistry.

Formula: C₁₂H₁₆N₆O₂S

InChI: InChI=1S/C12H16N6O2S/c1-14-10-7-11(17-12(15-2)16-10)18-21(19,20)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H3,14,15,16,17,18)

InChI key: InChIKey=JELFWSXQTXRMAJ-UHFFFAOYSA-N

SMILES: N(S(=O)(=O)C1=CC=C(N)C=C1)C=2C=C(NC)N=C(NC)N2

Synonyms:

• 4-Amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]benzenesulfonamide
• Benzenesulfonamide, 4-amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]-
• Ro 04-6790
• benzenesulfonamide, 4-amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]-, hydrochloride (1:2)

Ro 04-6790

CAS: 202466-68-0

Formula: C₁₂H₁₆N₆O₂S

Color and Shape: Solid

Molecular weight: 308.3594

Ref: IN-DA00288O

Ro 04-6790 dihydrochloride

CAS: 202466-68-0

Formula: C₁₂H₁₆N₆O₂S·2HCl

Molecular weight: 381.28

Ref: 7W-GK4010

Ro 04-6790 dihydrochloride

CAS: 202466-68-0

Ro 04-6790 is a cholinergic drug that binds to the 5-HT1A receptor. It has been shown to reduce the symptoms of depression in animal models and also increase locomotor activity. Ro 04-6790 has also been found to be an antagonist at 5-HT7 receptors and demonstrate receptor activity in the caudate putamen, a region of the brain that is involved in reward and emotional responses. In addition, Ro 04-6790 inhibits protein synthesis in cells by preventing translation initiation and inhibiting ribosomal translocation.

Formula: C₁₂H₁₆N₆O₂S·2HCl

Purity: Min. 95%

Molecular weight: 381.28 g/mol

Ref: 3D-CIA46668

Ro 04-6790

CAS: 202466-68-0

Ro 04-6790 is a 5-HT6 receptor antagonist.

Formula: C₁₂H₁₆N₆O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 308.36

Ref: TM-T23240