CAS 202475-60-3: 4-(4′-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline

Description: 4-(4′-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline, with the CAS number 202475-60-3, is a synthetic organic compound characterized by its quinazoline core structure, which is a bicyclic compound containing a benzene ring fused to a pyrimidine ring. This compound features a hydroxyl group and an amino group, contributing to its potential biological activity. The presence of methoxy groups at the 6 and 7 positions enhances its lipophilicity and may influence its interaction with biological targets. It is often studied for its potential pharmacological properties, including anti-cancer and anti-inflammatory activities. The compound's solubility, stability, and reactivity can vary based on environmental conditions such as pH and temperature. Additionally, its molecular structure allows for various modifications, which can lead to derivatives with altered biological activities. As with many quinazoline derivatives, it may act as a kinase inhibitor, making it of interest in medicinal chemistry and drug development.

Formula: C₁₆H₁₅N₃O₃

InChI: InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)

InChI key: InChIKey=HOZUXBLMYUPGPZ-UHFFFAOYSA-N

SMILES: OC1=CC=C(C=C1)NC=2N=CN=C3C=C(OC)C(OC)=CC32

Synonyms:

• 4-(4′-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline
• 4-(6,7-Dimethoxyquinazolin-4-Ylamino)Phenol
• 4-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenol
• Dde-9501
• Hi-P131
• Janex-1
• Janex-I
• Phenol, 4-[(6,7-dimethoxy-4-quinazolinyl)amino]-
• Whi-P 131
• Whi-P131

Phenol, 4-[(6,7-dimethoxy-4-quinazolinyl)amino]-

CAS: 202475-60-3

• Formula: C₁₆H₁₅N₃O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 297.3086

JANEX-1

CAS: 202475-60-3

• Purity: 98%
• Molecular weight: 297.31g/mol

JANEX-1

CAS: 202475-60-3

JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.

• Formula: C₁₆H₁₅N₃O₃
• Purity: 98% - 99.73%
• Color and Shape: Solid
• Molecular weight: 297.31

WHI-P 131

CAS: 202475-60-3

Inhibitor of Janus kinase JAK3; anti-cancer agent

• Formula: C₁₆H₁₅N₃O₃
• Purity: Min. 95%
• Molecular weight: 297.31 g/mol