CAS 202475-60-3

4-(4′-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline

Description:

4-(4′-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline, with the CAS number 202475-60-3, is a synthetic organic compound characterized by its quinazoline core structure, which is a bicyclic compound containing a benzene ring fused to a pyrimidine ring. This compound features a hydroxyl group and an amino group, contributing to its potential biological activity. The presence of methoxy groups at the 6 and 7 positions enhances its lipophilicity and may influence its interaction with biological targets. It is often studied for its potential pharmacological properties, including anti-cancer and anti-inflammatory activities. The compound's solubility, stability, and reactivity can vary based on environmental conditions such as pH and temperature. Additionally, its molecular structure allows for various modifications, which can lead to derivatives with altered biological activities. As with many quinazoline derivatives, it may act as a kinase inhibitor, making it of interest in medicinal chemistry and drug development.

Formula: C₁₆H₁₅N₃O₃

InChI: InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10/h3-9,20H,1-2H3,(H,17,18,19)

InChI key: InChIKey=HOZUXBLMYUPGPZ-UHFFFAOYSA-N

SMILES: N(C=1C2=C(C=C(OC)C(OC)=C2)N=CN1)C3=CC=C(O)C=C3

Synonyms:

• 4-(4′-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline
• 4-(6,7-Dimethoxyquinazolin-4-Ylamino)Phenol
• 4-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenol
• Dde-9501
• Hi-P131
• Janex-1
• Janex-I
• Phenol, 4-[(6,7-dimethoxy-4-quinazolinyl)amino]-
• Whi-P 131
• Whi-P131
• A JAK3 inhibitor
• WHI-P131(Janex 1)
• JAK3 INHIBITOR I
• JANEX-1;WHI-P131
• CS-2623
• WHI-P131, >98%

4-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenol

CAS: 202475-60-3

Formula: C₁₆H₁₅N₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 297.3086

Ref: IN-DA00289J

JANEX-1

CAS: 202475-60-3

JANEX-1

Purity: ≥98%

Molecular weight: 297.31g/mol

Ref: 54-BUP07220

JANEX-1

CAS: 202475-60-3

JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.

Formula: C₁₆H₁₅N₃O₃

Purity: 98% - 99.81%

Color and Shape: Solid

Molecular weight: 297.31

Ref: TM-T2045

JANEX-1

CAS: 202475-60-3

Purity: 98%

Molecular weight: 297.111

Ref: 10-F862107

WHI-P 131

CAS: 202475-60-3

Inhibitor of Janus kinase JAK3; anti-cancer agent

Formula: C₁₆H₁₅N₃O₃

Purity: Min. 95%

Molecular weight: 297.31 g/mol

Ref: 3D-FH59609