CAS 202592-23-2

(+)-JQ-1(carboxylic acid)

Description:

(+)-JQ-1 (carboxylic acid) is a chemical compound that belongs to a class of small molecules known for their role as inhibitors of the bromodomain and extraterminal (BET) family of proteins. These proteins are involved in the regulation of gene expression and play a significant role in various biological processes, including cancer progression. The compound is characterized by its ability to selectively bind to the bromodomains, thereby interfering with the interaction between acetylated lysines and BET proteins. This mechanism of action makes (+)-JQ-1 a valuable tool in research, particularly in studies related to epigenetics and cancer therapy. The carboxylic acid functional group contributes to its solubility and reactivity, influencing its pharmacokinetic properties. Additionally, (+)-JQ-1 has been studied for its potential therapeutic applications beyond oncology, including in inflammatory diseases and other conditions where BET proteins are implicated. Overall, (+)-JQ-1 (carboxylic acid) represents a significant advancement in the development of targeted therapies in molecular biology and medicinal chemistry.

Synonyms:

• 4-(4-chlorophenyl)-2
• 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-triMethyl-, (6S)-
• 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-triMethyl-, (6S)-
• JQ-1 (carboxylic acid)

6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-triMethyl-, (6S)-

CAS: 202592-23-2

Formula: C₁₉H₁₇ClN₄O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 400.8819

Ref: IN-DA0028BC

JQ-1 Carboxylic Acid

CAS: 202592-23-2

JQ-1 Carboxylic Acid

Purity: 98%

Molecular weight: 400.88g/mol

Ref: 54-OR1026194

JQ-1 (carboxylic acid)

CAS: 202592-23-2

JQ-1 (carboxylic acid)

Purity: ≥98%

Molecular weight: 400.88g/mol

Ref: 54-BUP10272

JQ-1 (carboxylic acid)

CAS: 202592-23-2

JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)

Formula: C₁₉H₁₇ClN₄O₂S

Purity: 99.14% - 99.9%

Color and Shape: Solid

Molecular weight: 400.88

Ref: TM-T5443

JQ1 Carboxylic Acid

CAS: 202592-23-2

Formula: C₁₉H₁₇ClN₄O₂S

Molecular weight: 400.88

Ref: 4Z-K-031044

JQ-1 (carboxylic acid)

CAS: 202592-23-2

Purity: 98%

Color and Shape: Solid

Molecular weight: 400.880004882813

Ref: 10-F862108

(+)-JQ1 carboxylic acid

Controlled Product

CAS: 202592-23-2

Inhibitor of bromodomain and extra terminal domain (BET) family proteins

Formula: C₁₉H₁₇ClN₄O₂S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 400.88 g/mol

Ref: 3D-FC164021

(+)-JQ1 Carboxylic Acid

Controlled Product

CAS: 202592-23-2

Formula: C₁₉H₁₇ClN₄O₂S

Color and Shape: Neat

Molecular weight: 400.882

Ref: TR-J216090