CAS 202801-92-1

Orexin B (rat, mouse)

Description:

Orexin B, also known as hypocretin-2, is a neuropeptide that plays a crucial role in regulating arousal, wakefulness, and appetite. It is primarily produced in the hypothalamus and is involved in various physiological processes, including energy homeostasis and the sleep-wake cycle. Orexin B is characterized by its specific amino acid sequence, which distinguishes it from other neuropeptides. The substance is known to bind to orexin receptors (OX1R and OX2R), influencing neurotransmitter release and promoting wakefulness. In animal models, such as rats and mice, orexin B has been studied for its implications in sleep disorders, obesity, and neurodegenerative diseases. Its structure includes a unique disulfide bond that contributes to its stability and biological activity. Research continues to explore the therapeutic potential of orexin B and its analogs in treating conditions like narcolepsy and other sleep-related disorders. Overall, orexin B is a vital component of the neuropeptide signaling system, with significant implications for both basic research and clinical applications.

Formula: C₁₂₆H₂₁₅N₄₅O₃₄S

Synonyms:

• Hypocretin2 (Rattus norvegicus)
• Orexin B (mouse)
• Rat orexin B
• H-Arg-Pro-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Asn-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
• L-Methioninamide,L-arginyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-leucyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-asparaginylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucy

Orexin B, Mouse, Rat

CAS: 202801-92-1

For cellular and molecular biology applications

Formula: C₁₂₆H₂₁₄N₄₅O₃₄S

Molecular weight: 2935.38

Ref: 02-J65275

Orexin B (mouse, rat)

CAS: 202801-92-1

Bachem ID: 4028264.

Formula: C₁₂₆H₂₁₅N₄₅O₃₄S

Purity: 90.5%

Color and Shape: White

Molecular weight: 2936.44

Ref: 01-4028264

H-ARG-PRO-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-ASN-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2

CAS: 202801-92-1

Formula: C₁₂₆H₂₁₅N₄₅O₃₄S

Purity: 98%

Molecular weight: 2936.4014

Ref: IN-DA00BCJJ

Orexin B, rat, mouse

CAS: 202801-92-1

Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.

Formula: C₁₂₆H₂₁₅N₄₅O₃₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 2936.45

Ref: TM-TP1045

Orexin-B (Rat, Mouse)

CAS: 202801-92-1

Orexin B is a neuropeptide that is produced by a small group of neurons in the hypothalamus, a region of the brain that plays a critical role in regulating various physiological functions, including sleep, appetite, and energy balance.
Orexin B, also known as hypocretin-2, plays a role in promoting wakefulness and arousal. Studies have shown that disruptions in the orexin system are associated with various sleep disorders, including narcolepsy and insomnia. In addition, orexin B has been shown to be involved in the regulation of appetite and energy metabolism, and is being explored as a potential target for the treatment of obesity and other metabolic disorders. Therefore, orexin B is an important neuropeptide and is an active area of research in neuroscience and medicine.

Formula: C₁₂₆H₂₁₅N₄₅O₃₄S

Purity: Min. 95%

Molecular weight: 2,936.4 g/mol

Ref: 3D-POR-4347-S

Orexin B (mouse, rat)

CAS: 202801-92-1

Please enquire for more information about Orexin B (mouse, rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₂₆H₂₁₅N₄₅O₃₄S

Purity: Min. 95%

Molecular weight: 2,936.4 g/mol

Ref: 3D-FO109203