CAS 202808-11-5

MRZ 2-514

CAS: 202808-11-5

MRZ 2-514 (8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one) is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with Ki

Formula: C₁₁H₆BrN₃O₃

Purity: 98.459%

Color and Shape: Solid

Molecular weight: 308.09

Ref: TM-T12110

MRZ 2-514

CAS: 202808-11-5

Formula: C₁₁H₆BrN₃O₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 308.0876

Ref: IN-DA01EOBC

MRZ 2-514

CAS: 202808-11-5

MRZ 2-514

Purity: ≥98%

Molecular weight: 308.09g/mol

Ref: 54-BUP12574

MRZ 2/514

CAS: 202808-11-5

MRZ 2/514 is a methoxy-substituted glycine derivative that is used as an antagonist. It has been shown to function as a competitive antagonist at the glycine site of the N-methyl-D-aspartate (NMDA) receptor, which is involved in neurotransmission. MRZ 2/514 has also been shown to block excitotoxicity in mice, which is caused by excessive stimulation of glutamate receptors. The methoxy group on MRZ 2/514 can be converted into a pyridyl group, which can form a dione with the amino acid histidine. This dione can then react with nitric oxide to form a nitrosated species that inhibits the activity of NMDA receptors.

Formula: C₁₁H₆BrN₃O₃

Purity: Min. 95%

Molecular weight: 308.09 g/mol

Ref: 3D-CIA80811