CAS 20300-44-1

Deglucohellebrin

Description:

Deglucohellebrin, with the CAS number 20300-44-1, is a chemical compound that belongs to the class of glycosides. It is derived from the plant species Helleborus, which is known for its medicinal properties. This compound is characterized by its glycosidic structure, which typically consists of a sugar moiety linked to a non-sugar aglycone. Deglucohellebrin is notable for its potential biological activities, including anti-inflammatory and analgesic effects, although specific mechanisms of action may vary. The compound is often studied for its pharmacological properties and potential therapeutic applications. In terms of physical properties, deglycosylated compounds like deglucohellebrin may exhibit different solubility and stability profiles compared to their glycosylated counterparts. As with many natural products, the extraction and purification processes can influence its availability and concentration in research settings. Overall, deglucohellebrin represents an interesting area of study within natural product chemistry and pharmacognosy.

Formula: C₃₀H₄₂O₁₀

InChI: InChI=1S/C30H42O10/c1-16-23(33)24(34)25(35)26(39-16)40-18-5-10-28(15-31)20-6-9-27(2)19(17-3-4-22(32)38-14-17)8-12-30(27,37)21(20)7-11-29(28,36)13-18/h3-4,14-16,18-21,23-26,33-37H,5-13H2,1-2H3/t16-,18-,19+,20-,21+,23-,24+,25+,26-,27+,28-,29-,30-/m0/s1

InChI key: InChIKey=HNNFRQFXBWSJBX-MTUTWWBMSA-N

SMILES: C(=O)[C@@]12[C@@]3([C@]([C@]4(O)[C@](C)(CC3)[C@H](CC4)C=5C=CC(=O)OC5)(CC[C@]1(O)C[C@@H](O[C@H]6[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O6)CC2)[H])[H]

Synonyms:

• Hellebrin, degluco-
• Bufa-20,22-dienolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3β,5β)-
• 5β-Bufa-20,22-dienolide, 3β-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxo-
• (3β,5β)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,14-dihydroxy-19-oxobufa-20,22-dienolide
• Deglucohellebrin

Desglucohellebrin

CAS: 20300-44-1

Desglucohellebrin is a natural product for research related to life sciences. The catalog number is TN5304 and the CAS number is 20300-44-1.

Formula: C₃₀H₄₂O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 562.65

Ref: TM-TN5304

Desglucohellebrin

CAS: 20300-44-1

Desglucohellebrin is a cardiac glycoside, which is a naturally occurring compound derived from the hellebore plant, specifically within the Ranunculaceae family. The primary action of desglucohellebrin is to influence the sodium-potassium pump (Na⁺/K⁺-ATPase) in cardiac cells. By inhibiting this pump, desglucohellebrin increases intracellular sodium levels, which indirectly elevates intracellular calcium concentrations through the sodium-calcium exchanger mechanism. This rise in calcium levels enhances myocardial contractility, leading to a positive inotropic effect while also potentially inducing changes in heart rhythm.

Formula: C₃₀H₄₂O₁₀

Purity: Min. 95%

Molecular weight: 562.6 g/mol

Ref: 3D-VAA30044